Synthetic biology of fungal natural products [PDF]
This work was supported by the DFG-funded excellence graduate school Jena School for Microbial Communication (JSMC; DJM, AAB), the collaborative research center (SFB) 1127 Chemical Mediators in Complex Biosystems (ChemBioSys—AAB, project B02) and the ...
Vito Valiante +7 more
core +1 more source
High-throughput format for the phenotyping of fungi on solid substrates
Filamentous fungi naturally grow on solid surfaces, yet most genetic and biochemical analyses are still performed in liquid cultures. Here, we report a multiplexing platform using high-throughput photometric continuous reading that allows parallel ...
David Cánovas +3 more
doaj +1 more source
Do small RNAs unlock the below ground microbiome-plant interaction mystery?
Over the past few decades, regulatory RNAs, such as small RNAs (sRNAs), have received increasing attention in the context of host-microbe interactions due to their diverse roles in controlling various biological processes in eukaryotes.
Roshan Regmi +8 more
doaj +1 more source
Summary We present genome‐wide gene expression patterns as a time series through the infection cycle of the fungal pine needle blight pathogen, Dothistroma septosporum, as it invades its gymnosperm host, Pinus radiata. We determined the molecular changes
R. Bradshaw +8 more
semanticscholar +1 more source
Molecular Bases and Genetic Design of Rice Disease Resistance for Optimized Yield and Sustainable Agriculture. [PDF]
This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Hou X, Cui Y, Ding C, Qian Q, Ren D.
europepmc +2 more sources
Fungal secondary metabolism: regulation, function and drug discovery
One of the exciting movements in microbial sciences has been a refocusing and revitalization of efforts to mine the fungal secondary metabolome. The magnitude of biosynthetic gene clusters (BGCs) in a single filamentous fungal genome combined with the ...
N. Keller
semanticscholar +1 more source
Cloning and characterization of novel methylsalicylic acid synthase gene involved in the biosynthesis of isoasperlactone and asperlactone in Aspergillus westerdijkiae [PDF]
Aspergillus westerdijkiae is the main producer of several biologically active polyketide metabolites including isoasperlactone and asperlactone. A 5298 bp polyketide synthase gene ‘‘aomsas” has been cloned in Aspergillus westerdijkiae by using gene ...
Atoui, Ali +10 more
core +1 more source
Analysis of miRNAs in Two Wheat Cultivars Infected With Puccinia striiformis f. sp. tritici
MicroRNAs are small RNAs that regulate gene expression in eukaryotes. In this study, we analyzed the small RNA profiles of two cultivars that exhibit different reactions to stripe rust infection: one susceptible, the other partially resistant.
Sowmya R. Ramachandran +3 more
doaj +1 more source
This study demonstrates the development of a humanized luciferase imaging reporter based on a recently discovered mushroom luciferase (Luz) from Neonothopanus nambi.
Aaiyas Mujawar +10 more
doaj +1 more source
Expression of the Avirulence Gene Avr9 of the Fungal Tomato Pathogen Cladosporium fulvum Is Regulated by the Global Nitrogen Response Factor NRF1 [PDF]
Here we describe the role of the Cladosporium fulvum nitrogen response factor 1 (Nrf1) gene in regulation of the expression of avirulence gene Avr9 and virulence on tomato. The Nrf1 gene, which was isolated by a polymerase chain reaction-based strategy, is predicted to encode a protein of 918 amino acid residues.
Pérez-García, A. +4 more
openaire +3 more sources

