Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Harnessing the Tet-Off system for effective gene silencing in Magnaporthe oryzae
Rice blast is the most serious fungal disease affecting rice production worldwide. Studying gene function in the rice-blast fungus Magnaporthe oryzae often presents significant challenges, especially if it involves loci that are essential for the fungal ...
Zhenyu Fang +18 more
doaj +1 more source
Transcriptional Profiles Uncover Aspergillus flavus-Induced Resistance in Maize Kernels
Aflatoxin contamination caused by the opportunistic pathogen A. flavus is a major concern in maize production prior to harvest and through storage.
Zhi-Yuan Chen +5 more
doaj +1 more source
Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren +20 more
wiley +1 more source
Transcriptome analysis of silkworm, Bombyx mori, during early response to Beauveria bassiana challenges. [PDF]
Host-pathogen interactions are complex processes and it is a central challenge to reveal these interactions. Fungal infection of silkworm, Bombyx mori, may induce a variety of responsive reaction. However, little is known about the molecular mechanism of
Chengxiang Hou +7 more
doaj +1 more source
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu +5 more
wiley +1 more source
The Ustilago maydis Cys2His2‐type zinc finger transcription factor Mzr1 regulates fungal gene expression during the biotrophic growth stage [PDF]
SummaryThe smut fungus Ustilago maydis establishes a biotrophic relationship with its host plant maize to progress through sexual development. Here, we report the identification and characterization of the Cys2His2‐type zinc finger protein Mzr1 that functions as a transcriptional activator during host colonization. Expression of the U.
Zheng, Y. +6 more
openaire +3 more sources
A biomimetic artificial extracellular matrix is assembled directly on Pseudomonas fluorescens by co‐assembling amyloid‐like lysozyme and alginate at the cell surface. This conformal nanocoating acts as both a hydration buffer and a physiological priming layer, markedly enhancing desiccation tolerance, seed adhesion, storage stability, and biocontrol ...
Yuanyuan Wang +5 more
wiley +1 more source
The transcriptional repressor Ssn6 modulates phase separation to regulate fungal gene expression
ABSTRACT The transcriptional regulation of cell fate plays a central role in eukaryotic cell differentiation. In the human fungal pathogen Candida albicans , the white-to-opaque cell fate switch is controlled by an ...
Maureen A. Dowell +3 more
openaire +1 more source
High Tree Species Diversity Promotes Thermal Enhancement Response of Microbial Carbon Use Efficiency
ABSTRACT Predicting soil carbon dynamics under warming is constrained by limited understanding of microbial thermal adaptation, particularly whether microbial carbon use efficiency (CUE) can adapt to warming and how plant diversity modulates this response. Using soils from a natural tree species diversity gradient in a subtropical forest, we combined a
Pengpeng Duan +11 more
wiley +1 more source

