Results 71 to 80 of about 544,702 (294)

Chromatin-Mediated Regulation of Genome Plasticity in Human Fungal Pathogens

Genes, 2019
Human fungal pathogens, such as Candida albicans, Aspergillus fumigatus and Cryptococcus neoformans, are a public health problem, causing millions of infections and killing almost half a million people annually. The ability of these pathogens to colonise
A. Buscaino
semanticscholar   +1 more source

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

Advanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang   +21 more
wiley   +1 more source

Transcriptome Analysis Reveals Candidate Genes for Light Regulation of Elsinochrome Biosynthesis in Elsinoë arachidis

Microorganisms
Light regulation is critical in fungal growth, development, morphogenesis, secondary metabolism, and the biological clock. The fungus Elsinoë arachidis is known to produce the mycotoxin Elsinochrome (ESC), a key factor contributing to its pathogenicity ...
Dan Liu, Jingzi Piao, Yang Li, Haiwen Guan, Jingwen Hao, Rujun Zhou   +5 more
doaj   +1 more source

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

Advanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan, Manyun Mao, Jiaan Zhang, Zhimin Duan, JiaNing Wang, Yujie Chen, Sihan Chen, Chuting Liang, Xvyue Zhou, Songmei Geng, Min Li, Xu Chen, Ni Lian   +12 more
wiley   +1 more source

Harnessing the Tet-Off system for effective gene silencing in Magnaporthe oryzae

Frontiers in Plant Science
Rice blast is the most serious fungal disease affecting rice production worldwide. Studying gene function in the rice-blast fungus Magnaporthe oryzae often presents significant challenges, especially if it involves loci that are essential for the fungal ...
Zhenyu Fang, Zhenyu Fang, Fan Yang, Yongge Ma, Yongge Ma, Yan Cai, Yan Cai, Xin Chen, Xin Chen, Shiyu Yang, Shiyu Yang, Abubakar Yakubu Saddeeq, Abubakar Yakubu Saddeeq, Zonghua Wang, Zonghua Wang, Zonghua Wang, Naweed I. Naqvi, Wenhui Zheng, Wenhui Zheng   +18 more
doaj   +1 more source

Transcriptional Profiles Uncover Aspergillus flavus-Induced Resistance in Maize Kernels

Toxins, 2011
Aflatoxin contamination caused by the opportunistic pathogen A. flavus is a major concern in maize production prior to harvest and through storage.
Zhi-Yuan Chen, Abebe Menkir, Jiujiang Yu, Deepak Bhatnagar, Robert L. Brown, Meng Luo   +5 more
doaj   +1 more source

High hydrostatic pressure harnesses the biosynthesis of secondary metabolites via the regulation of polyketide synthesis genes of hadal sediment-derived fungi

Frontiers in Microbiology, 2023
Deep-sea fungi have evolved extreme environmental adaptation and possess huge biosynthetic potential of bioactive compounds. However, not much is known about the biosynthesis and regulation of secondary metabolites of deep-sea fungi under extreme ...
Ludan Deng, Maosheng Zhong, Yongqi Li, Guangzhao Hu, Changhao Zhang, Qingqing Peng, Zhizhen Zhang, Jiasong Fang, Xi Yu   +8 more
doaj   +1 more source

Complex epigenetic regulation of alkaloid biosynthesis and host interaction by heterochromatin protein I in a fungal endophyte-plant symbiosis.

Fungal Genetics and Biology, 2019
Epichloë festucae forms mutualistic symbiotic interactions with grasses of the Lolium and Festuca genera. Protection from insect and mammalian herbivory are the best-documented host benefits of these associations.
Tetsuya Chujo, Yonathan Lukito, Carla J. Eaton, P. Dupont, L. Johnson, David J. Winter, M. Cox, B. Scott   +7 more
semanticscholar   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Transcriptome analysis of silkworm, Bombyx mori, during early response to Beauveria bassiana challenges. [PDF]

PLoS ONE, 2014
Host-pathogen interactions are complex processes and it is a central challenge to reveal these interactions. Fungal infection of silkworm, Bombyx mori, may induce a variety of responsive reaction. However, little is known about the molecular mechanism of
Chengxiang Hou, Guangxing Qin, Ting Liu, Tao Geng, Kun Gao, Zhonghua Pan, Heying Qian, Xijie Guo   +7 more
doaj   +1 more source