Results 161 to 170 of about 282,173 (256)

Role of circulating exosomal biomarkers and their diagnostic accuracy in pancreatic cancer

JGH Open, Volume 7, Issue 1, Page 30-39, January 2023., 2023
This systematic review aims to evaluate the current literature involving pancreatic cancer patient groups in search of highly accurate exosomal biomarkers. We reviewed 9 studies which involved 565 participants (331 PC and 234 controls). The mRNA panel (ARG1, CD63, CK18, Erbb3, GAPDH, H3F3A, KRAS, and ODC1) and GPC1 reported the highest performing ...
Menazir Sha, Basir Kunduzi, Saied Froghi, Alberto Quaglia, Brian Davidson, Giuseppe K Fusai   +5 more
wiley   +1 more source

ROCK2 Downregulation in Pediatric Medulloblastoma Increases Migration and Predicts the Involvement of SHH Non-canonical Signaling. [PDF]

Yale J Biol Med
Hakime RG, Nagano LFP, Brassesco MS.
europepmc   +1 more source

Methodology of high‐dimensional flow cytometry in monitoring immune microenvironment of pituitary neuroendocrine tumors

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Characterization of the tumor immune microenvironment (TIME) of pituitary neuroendocrine tumors (PitNETs) is crucial for understanding the behavior of different types of PitNETs and identification of possible causes of their aggressiveness, rapid growth, and resistance to therapy.
Marina Yu Loguinova, Valeria V. Mazeeva, Daria V. Lisina, Elena N. Zakharova, Alyona V. Sorokina, Lilya U. Dzhemileva, Andrei Yu Grigoriev, Alexandra S. Shutova, Ekaterina A. Pigarova, Larisa K. Dzeranova, Galina A. Melnichenko, Natalia G. Mokrysheva, Sergei A. Rumiantsev, Vladimir P. Chekhonin   +13 more
wiley   +1 more source

The peritumoral brain zone in glioblastoma: where we are and where we are going

Journal of Neuroscience Research, Volume 101, Issue 2, Page 199-216, February 2023., 2023
Abstract Glioblastoma (GBM) is the most aggressive and invasive primary brain tumor. Current therapies are not curative, and patients' outcomes remain poor with an overall survival of 20.9 months after surgery. The typical growing pattern of GBM develops by infiltrating the surrounding apparent normal brain tissue within which the recurrence is ...
Martina Giambra, Andrea Di Cristofori, Silvia Valtorta, Roberto Manfrellotti, Vittorio Bigiogera, Gianpaolo Basso, Rosa Maria Moresco, Carlo Giussani, Angela Bentivegna   +8 more
wiley   +1 more source

A single-cell atlas of Schwannoma across genetic backgrounds and anatomic locations. [PDF]

Genome Med
Gonzalez Castro LN, Gavish A, Bussema L, Mount CW, Neftel C, Nomura M, Chiocca EA, Bi WL, Arnaout O, Barker FG, Brown JM, Jordan JT, Batchelor TT, Stemmer-Rachamimov A, Plotkin SR, Tirosh I, Suvà ML.   +16 more
europepmc   +1 more source

Effects of glepaglutide, a long‐acting glucagon‐like peptide‐2 analog, on intestinal morphology and perfusion in patients with short bowel syndrome: Findings from a randomized phase 2 trial

Journal of Parenteral and Enteral Nutrition, Volume 47, Issue 1, Page 140-150, January 2023., 2023
Abstract Background The proadaptive effects of glucagon‐like peptide‐2 (GLP‐2) include stimulation of intestinal mucosal growth as well as intestinal blood flow and angiogenesis. We have recently reported that daily subcutaneous injections of glepaglutide, a long‐acting GLP‐2 analog, improved intestinal absorptive function in patients with short bowel ...
Rahim M. Naimi, Mark K. Hvistendahl, Steen S. Poulsen, Hannelouise Kissow, Jens Pedersen, Nikolaj A. Nerup, Rikard Ambrus, Michael P. Achiam, Lars B. Svendsen, Palle B. Jeppesen   +9 more
wiley   +1 more source

Hypoxia-associated genes as predictors of outcomes in gastric cancer: a genomic approach. [PDF]

Front Immunol
Yang S, Jiang Y, Yang Z.
europepmc   +1 more source

A translational perspective of the malignant hematopoietic proteoglycome. [PDF]

Cell Biosci
Borghini N, Lazzaretti M, Lunghi P, Malpeli G, Barbi S, Perris R.   +5 more
europepmc   +1 more source

Comprehensive Transcriptomic Analysis Reveals Cell-Type-Specific Roles of Human Odorant Receptors in Glioblastoma and the Tumor Microenvironment. [PDF]

Int J Mol Sci
Cho HJ, Yeo DJ, Yang H, Koo J.
europepmc   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source