Aggressive Head and Neck Squamous Cell Carcinoma in the Setting of GATA2 Deficiency
ABSTRACT Background GATA2 deficiency is a rare genetic disorder associated with hematologic, infectious, and neoplastic complications. We report a case of a patient with GATA2 deficiency who developed aggressive squamous cell carcinoma (SCC) of the head and neck, an atypical manifestation of this condition.
Brejjette Aljabi+3 more
wiley +1 more source
Molecular Abnormalities and Carcinogenesis in Barrett's Esophagus: Implications for Cancer Treatment and Prevention. [PDF]
de Melo Viana TC+7 more
europepmc +1 more source
Bitter Taste Receptor Agonists Induce Apoptosis in Papillary Thyroid Cancer
ABSTRACT Background Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy, with a 20% recurrence rate. Bitter taste receptors (T2Rs) and their genes (TAS2Rs) may regulate survival in solid tumors. This study examined T2R expression and function in PTC cells.
Kimberly Wei+6 more
wiley +1 more source
Aberrant expression of human endogenous retrovirus K9-derived elements is associated with better clinical outcome of acute myelocytic leukemia. [PDF]
Yanagiya R+3 more
europepmc +1 more source
Deciphering novel mitochondrial signatures: multi-omics analysis uncovers cross-disease markers and oligodendrocyte pathways in Alzheimer's disease and glioblastoma. [PDF]
Xu X+7 more
europepmc +1 more source
The Oncoprotein Mucin 1 in Pancreatic Cancer Onset and Progression: Potential Clinical Implications. [PDF]
Dieli R+10 more
europepmc +1 more source
Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets. [PDF]
Vinel C+7 more
europepmc +1 more source
Downregulated Regucalcin Expression Induces a Cancer-like Phenotype in Non-Neoplastic Prostate Cells and Augments the Aggressiveness of Prostate Cancer Cells: Interplay with the G Protein-Coupled Oestrogen Receptor? [PDF]
Fonseca LRS+7 more
europepmc +1 more source
Malignant Cells Beyond the Tumor Core: The Non-Negligible Factor to Overcome the Refractory of Glioblastoma. [PDF]
Zhou Y+11 more
europepmc +1 more source
Prognostic and clinicopathological roles of circular RNA expression in chemoresistance in head and neck squamous cell carcinoma: a systematic review. [PDF]
Das SK, Khasbage S, Mishra A, Jee B.
europepmc +1 more source