Results 21 to 30 of about 7,007,953 (262)
hZIP1 zinc uptake transporter down regulation and zinc depletion in prostate cancer
Molecular Cancer, 2005 Background The genetic and molecular mechanisms responsible for and associated with the development and progression of prostate malignancy are largely unidentified.
Kajdacsy-Balla André +7 more
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Phosphorylation-Mediated Regulation of Alternative Splicing in Cancer
International Journal of Cell Biology, 2013 Alternative splicing (AS) is one of the key processes involved in the regulation of gene expression in eukaryotic cells. AS catalyzes the removal of intronic sequences and the joining of selected exons, thus ensuring the correct processing of the primary
Chiara Naro, Claudio Sette
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Cancer Cell International, 2006 Background p27(Kip1) is a cyclin-dependent kinase inhibitor. When up-regulated, p27 inhibits G1-to-S phase transition of the cell cycle. This report addresses the question of whether various nutritional and chemopreventive anti-cancer agents up-regulate ...
Eto Isao
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Circular RNA as An Epigenetic Regulator in Chronic Liver Diseases
Cells, 2021 Circular RNA (circRNA) is a type of non-coding RNA characterized by a covalently closed continuous loop. CircRNA is generated by pre-mRNA through back-splicing and is probably cleared up by extracellular vesicles.
Xianhui Zeng +4 more
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Genomics and proteomics approaches to the study of cancer-stroma interactions
BMC Medical Genomics, 2010 Background The development and progression of cancer depend on its genetic characteristics as well as on the interactions with its microenvironment.
Fukuyama Erica E +14 more
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PRDM Proteins: Molecular Mechanisms in Signal Transduction and Transcriptional Regulation
Biology, 2013 PRDM (PRDI-BF1 and RIZ homology domain containing) protein family members are characterized by the presence of a PR domain and a variable number of Zn-finger repeats.
Bruno Moncharmont +3 more
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Biology, 2023 Neuroblastoma represents a neoplastic expansion of neural crest cells in the developing sympathetic nervous system and is childhood’s most common extracranial solid tumor.
Mónica Leticia Martínez-Pacheco +2 more
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Functions and mechanisms of miR-650 in human diseases
Frontiers in Molecular BiosciencesMicroRNAs (miRNAs) are endogenous, single-stranded, small non-coding RNAs that play central roles in gene expression regulation. Among them, miR-650 has received increasing attention over the past decade because it regulates cell proliferation ...
Qingmiao Shi, Chengran Gao, Chen Xue
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Analysis of apoptosis related genes in nurses exposed to anti-neoplastic drugs
BMC Pharmacology and Toxicology, 2019 Background Anti-neoplastic agents are widely used in the treatment of cancer and some non-neoplastic diseases. These drugs have been proved to be carcinogens, teratogens, and mutagens.
Maral Ramazani +5 more
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Transcriptional Factors in the Cochlea Within the Inner Ear
Journal of Pharmacological Sciences, 2005 Differential regulation of gene expression by transcription factors is widely viewed as one of the principal mechanisms guiding development. Although numerous DNA binding proteins have been identified in various tissues, the role of individual ...
Reiko Nagashima +3 more
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