Results 11 to 20 of about 7,007,953 (262)

A systems biology design and implementation of novel bioinformatics software tools for high throughput gene expression analysis [PDF]

, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Microarray technology has revolutionized the field of molecular biology by offering an efficient and cost effective platform for the simultaneous ...
Khan, Mohsin Amir Faiz
core   +7 more sources

Stochastic neural network models for gene regulatory networks [PDF]

, 2003
Recent advances in gene-expression profiling technologies provide large amounts of gene expression data. This raises the possibility for a functional understanding of genome dynamics by means of mathematical modelling.
Tian, T., Burrage, K.
core   +9 more sources

Regulation of Normal and Neoplastic Proliferation and Metabolism by the Extended Myc Network

Cells, 2022
The Myc Network, comprising a small assemblage of bHLH-ZIP transcription factors, regulates many hundreds to thousands of genes involved in proliferation, energy metabolism, translation and other activities. A structurally and functionally related set of
Edward V. Prochownik
doaj   +1 more source

Chromosomal proteins and the regulation of gene expression in normal and neoplastic cells

Leukemia Research, 1977
Leukemia Research 1 (1977) 351-384.
J. Hillis Miller Health Center, University of Florida, Gainesville, FL 32610, U.S.A. ( host institution ), Stein, Gary S., Stein, Janet L., Thomson, Judith A.   +3 more
openaire   +2 more sources

Increased Expression of the EZH2 Polycomb Group Gene in BMI-1-Positive Neoplastic Cells during Bronchial Carcinogenesis [PDF]

, 2004
Polycomb group (PcG) genes are responsible for maintenance of cellular identity and contribute to regulation of the cell cycle. Recent studies have identified several PcG genes as oncogenes, and a role for PcG proteins in human oncogenesis is suspected ...
Richard G.A.B. Sewalt, Folkert J. van Kemenade, Roderick H.J. Breuer, Peter J.F. Snijders, Sutedja, Thomas G., van Kemenade, Folkert J., Smit, E.F., Arie P. Otte, Postmus, P.E., Otte, A.P., Raaphorst, F.M., Frank M. Raaphorst, Breuer, Roderick H.J., Meijer, C.J., van Kemenade, F.J., Sewalt, Richard G.A.B., Postmus, Pieter E., Thomas G. Sutedja, Otte, Arie P., Sutedja, T.G., Smit, Egbert F., Meijer, Chris J.L.M., Chris J.L.M. Meijer, Egbert F. Smit, Snijders, Peter J.F., Sewalt, R.G.A.B., Raaphorst, Frank M., Snijders, P.J.F., Breuer, R.H., Pieter E. Postmus   +29 more
core   +2 more sources

Rhythmic diel pattern of gene expression in juvenile maize leaf. [PDF]

, 2011
Co-expressed genes belonging to individual clusters are likely to be regulated by common mechanisms. The nocturnal phase of the diurnal cycle involves gross induction of fundamental biochemical processes and should be studied more thoroughly than was ...
Paweł Siedlecki, Jerzy Tiuryn, Biecek Przemysław, Alicja Sobkowiak, Tiuryn, Jerzy, Jan Fronk, Tiuryn Jerzy, Jończyk, Maciej, Maciej Jończyk, Paweł Sowiński, Jończyk Maciej, Sowiński, Paweł, Siedlecki Paweł, Fronk Jan, Fronk, Jan, Joanna Trzcinska-Danielewicz, Biecek, Przemysław, Sowiński Paweł, Sobkowiak Alicja, Sobkowiak, Alicja, Trzcinska-Danielewicz Joanna, Przemysław Biecek, Siedlecki, Paweł, Trzcinska-Danielewicz, Joanna   +23 more
core   +2 more sources

DICER1 RNase IIIb domain mutations trigger widespread miRNA dysregulation and MAPK activation in pediatric thyroid cancer

Frontiers in Endocrinology, 2023
DICER1 is a highly conserved RNase III endoribonuclease essential for the biogenesis of single-stranded mature microRNAs (miRNAs) from stem-loop precursor miRNAs.
Julio C. Ricarte-Filho, Victoria Casado-Medrano, Erin Reichenberger, Zachary Spangler, Michele Scheerer, Amber Isaza, Julia Baran, Tasleema Patel, Suzanne P. MacFarland, Suzanne P. MacFarland, Garrett M. Brodeur, Garrett M. Brodeur, Garrett M. Brodeur, Douglas R. Stewart, Zubair Baloch, Andrew J. Bauer, Andrew J. Bauer, Jonathan D. Wasserman, Aime T. Franco, Aime T. Franco, Aime T. Franco   +20 more
doaj   +1 more source

p53: From Fundamental Biology to Clinical Applications in Cancer

Biology, 2022
p53 tumour suppressor gene is our major barrier against neoplastic transformation. It is involved in many cellular functions, including cell cycle arrest, senescence, DNA repair, apoptosis, autophagy, cell metabolism, ferroptosis, immune system ...
Maurizio Capuozzo, Mariachiara Santorsola, Marco Bocchetti, Francesco Perri, Marco Cascella, Vincenza Granata, Venere Celotto, Oreste Gualillo, Alessia Maria Cossu, Guglielmo Nasti, Michele Caraglia, Alessandro Ottaiano   +11 more
doaj   +1 more source

Transcriptomic effects of di-(2-ethylhexyl)-phthalate in Syrian hamster embryo cells: an important role of early cytoskeleton disturbances in carcinogenesis?

BMC Genomics, 2011
Background Di-(2-ethylhexyl)-phthalate (DEHP) is a commonly used plasticizer in polyvinylchloride (PVC) formulations and a potentially non-genotoxic carcinogen.
Atienzar Franck, Poupin Pascal, Landkocz Yann, Vasseur Paule   +3 more
doaj   +1 more source

The Survivin −31 Snp in Human Colorectal Cancer Correlates with Survivin Splice Variant Expression and Improved Overall Survival

Analytical Cellular Pathology, 2010
Background: Survivin is involved in the regulation of cell division and survival, two key processes in cancer. The majority of studies on survivin in colorectal cancer (CRC) have focused on protein expression and less is known about the expression of ...
Anna G. Antonacopoulou, Konstantina Floratou, Vasiliki Bravou, Anastasia Kottorou, Fotinos-Ioannis Dimitrakopoulos, Stella Marousi, Michalis Stavropoulos, Agelos K. Koutras, Chrisoula D. Scopa, Haralabos P. Kalofonos   +9 more
doaj   +1 more source