Results 231 to 240 of about 472,464 (265)
Some of the next articles are maybe not open access.
Regulation of HIV expression by viral genes and cytokines
Journal of Leukocyte Biology, 1994Abstract The human immunodeficiency virus (HIV) is the causative agent of the acquired immunodeficiency syndrome (AIDS), a leading cause of death among young individuals. As a complex pathogenic retrovirus, HIV is characterized in vitro and in vivo by the ability to establish either a latent or productive infection of CD4+ T lymphocytes ...
VICENZI E, POLI , GUIDO
openaire +3 more sources
Oxygen, a regulator of viral gene expression?
Current Research in Translational Medicine, 2016International ...
Morinet, F. +5 more
openaire +4 more sources
Translational regulation of hepatitis B viral gene expression
Journal of Gastroenterology and Hepatology, 1993AbstractAt least five species of unspliced mRNA of the hepatitis B virus (HBV), which are 3.5, 3.4, 2.4, 2.1 and 0.8 kb, have been identified. To study this amount of HBV proteins they were translationally regulated and both in vitro and in vivo experiments performed. The four in vitro synthesized RNA corresponding to the 2.1, 2.4, 3.4, and 3.5 kb mRNA,
S. J. LO, S. Y. SHEU, C‐G. LIN
openaire +1 more source
Bovine papillomavirus E2 gene regulates expression of the viral E5 transforming gene
Journal of Virology, 1988We have performed transient-expression experiments with CV1 monkey kidney cells to investigate the role of the bovine papillomavirus type 1 (BPV1) E2 gene in the regulation of the E5 transforming gene. Direct analysis of the 7-kilodalton open reading frame (ORF) E5 protein and measurements of the expression of an E5-chloramphenicol acetyltransferase ...
S S, Prakash +4 more
openaire +2 more sources
Viral-based gene delivery and regulated gene expression for targeted cancer therapy
Expert Opinion on Drug Delivery, 2009Cancer is both a major health concern and a care-cost issue in the US and the rest of the world. It is estimated that there will be a total of 1,479,350 new cancer cases and 562,340 cancer deaths in 2009 within the US alone. One of the major obstacles in cancer therapy is the ability to target specifically cancer cells. Most existing chemotherapies and
Yi, Lu, Chikezie O, Madu
openaire +2 more sources
Splicing and the Regulation of Viral Gene Expression
1981Spliced viral mRNA species are synthesized in permissive cells infected by several viruses that possess DNA genomes, such as the parvoviruses, papovaviruses, and adenoviruses, or by those whose life cycle depends on synthesis of a double-stranded DNA copy of an RNA genome, the retroviruses.
openaire +2 more sources
Circadian Regulation of a Viral Gene Promoter in Live Transgenic Mice Expressing Firefly Luciferase
Molecular Imaging and Biology, 2005This study was conducted to test for possible circadian control of viral infection in live animals using bioluminescence imaging of a firefly luciferase transgene.Transgenic mice expressing the firefly luciferase gene under the control of the promoter and enhancer of the human cytomegalovirus major immediate-early gene (CMV::luc) were examined through ...
Anne M, Collaco +4 more
openaire +2 more sources
SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells
Nature, 2005MicroRNAs (miRNAs) are small (approximately 22-nucleotide) RNAs that in lower organisms serve important regulatory roles in development and gene expression, typically by forming imperfect duplexes with target messenger RNAs. miRNAs have also been described in mammalian cells and in infections with Epstein-Barr virus (EBV), but the function of most of ...
Christopher S, Sullivan +4 more
openaire +2 more sources
Regulation of viral and cellular gene expression in sensory neurons.
Gene therapy, 1996Herpes simplex virus (HSV) establishes latent infections of neuronal cells but replicates readily in other cell types. This effect is dependent upon the presence of the inhibitory cellular transcription factor Oct-2 in neuronal cells. This factor inhibits the viral immediate-early gene promoters by at least two distinct mechanisms.
openaire +1 more source
2008
Mouse embryonal carcinoma (EC) cells, also called teratocarcinoma stem cells, are nonpermissive for polyomavirus growth, whereas differentiated derivatives of the cells are permissive. Mutant viruses capable of growing in EC cells can be isolated. They have genomic alterations within the viral enhancer, which is required for viral gene expression and ...
openaire +2 more sources
Mouse embryonal carcinoma (EC) cells, also called teratocarcinoma stem cells, are nonpermissive for polyomavirus growth, whereas differentiated derivatives of the cells are permissive. Mutant viruses capable of growing in EC cells can be isolated. They have genomic alterations within the viral enhancer, which is required for viral gene expression and ...
openaire +2 more sources