Results 261 to 270 of about 698,006 (308)

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Identification of Fish Interferon-Stimulated Genes and Their Antiviral Mechanisms. [PDF]

Viruses
Yang E.
europepmc   +1 more source

GNL3 Orchestrates AR Transcriptional Programs to Drive Castration‐Resistant Prostate Cancer and Immune Evasion

Advanced Science, EarlyView.
GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang, Tin Long Cheong, Nitin Narwade, Dandan Dong, Mokan Deng, Zhengqiang Miao, Zhaoqiang Ding, Wenchao Li, Kate Man Kei Lei, Gong‐Hong Wei, Terence Chuen Wai Poon, Chu‐Xia Deng, Edwin Cheung   +12 more
wiley   +1 more source

Long Non-Coding RNA Encoded by Infectious Bronchitis Virus Facilitates Viral Replication via Direct Interaction with G3BP2 and Expression Regulation of a Novel Host MicroRNA. [PDF]

Vet Sci
Zhang M, Cai Z, An H, He R, Zhang S, Fang S.   +5 more
europepmc   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Adaptation of lentiviral vectors for viral gene therapy and their impact on host cell biology. [PDF]

J Transl Med
Kaiser CW, Rouchka EC, Smith ML.
europepmc   +1 more source

Hepatitis virus-associated B cell non-Hodgkin's lymphoma involves dysregulated epigenetic and RNA-mediated regulatory gene expression and altered snoRNA transcription. [PDF]

Sci Rep
Henning AN, Budeebazar M, Boldbaatar D, Yagaanbuyant D, Duger D, Batsukh K, Muccilli S, Pardoe J, Perinet L, Conway O, Owusu-Ansah D, Robichaux K, Baumann R, Alter HJ, Dashdorj N, De Giorgi V.   +15 more
europepmc   +1 more source

Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review). [PDF]

Mol Med Rep
Lee B, Son C, Eom S, Li Y, Kim SH, Park J.   +5 more
europepmc   +1 more source

The X Factor in Immunity: Sex Differences Shaped by the X Chromosome. [PDF]

Immunol Rev
Radovanovic KB, Wynalda M, Anguera MC, Anguera MC.   +3 more
europepmc   +1 more source