Results 271 to 280 of about 698,006 (308)

Downregulation of the host ribonucleotide reductase subunit M2 via the Wnt/β-catenin pathway is a novel mechanism for duck plague virus replication and a potential antiviral target. [PDF]

open access: yesPoult Sci
Yang Q   +16 more
europepmc   +1 more source
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Viral miRNA regulation of host gene expression

Seminars in Cell & Developmental Biology, 2023
Viruses have evolved a multitude of mechanisms to combat barriers to productive infection in the host cell. Virally-encoded miRNAs are one such means to regulate host gene expression in ways that benefit the virus lifecycle. miRNAs are small non-coding RNAs that regulate protein expression but do not trigger the adaptive immune response, making them ...
Nicole L, Diggins, Meaghan H, Hancock
openaire   +2 more sources

Regulation of HIV expression by viral genes and cytokines

Journal of Leukocyte Biology, 1994
Abstract The human immunodeficiency virus (HIV) is the causative agent of the acquired immunodeficiency syndrome (AIDS), a leading cause of death among young individuals. As a complex pathogenic retrovirus, HIV is characterized in vitro and in vivo by the ability to establish either a latent or productive infection of CD4+ T lymphocytes ...
VICENZI E, POLI , GUIDO
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Oxygen, a regulator of viral gene expression?

Current Research in Translational Medicine, 2016
International ...
Morinet, F.   +5 more
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Translational regulation of hepatitis B viral gene expression

Journal of Gastroenterology and Hepatology, 1993
AbstractAt least five species of unspliced mRNA of the hepatitis B virus (HBV), which are 3.5, 3.4, 2.4, 2.1 and 0.8 kb, have been identified. To study this amount of HBV proteins they were translationally regulated and both in vitro and in vivo experiments performed. The four in vitro synthesized RNA corresponding to the 2.1, 2.4, 3.4, and 3.5 kb mRNA,
S. J. LO, S. Y. SHEU, C‐G. LIN
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Bovine papillomavirus E2 gene regulates expression of the viral E5 transforming gene

Journal of Virology, 1988
We have performed transient-expression experiments with CV1 monkey kidney cells to investigate the role of the bovine papillomavirus type 1 (BPV1) E2 gene in the regulation of the E5 transforming gene. Direct analysis of the 7-kilodalton open reading frame (ORF) E5 protein and measurements of the expression of an E5-chloramphenicol acetyltransferase ...
S S, Prakash   +4 more
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Viral-based gene delivery and regulated gene expression for targeted cancer therapy

Expert Opinion on Drug Delivery, 2009
Cancer is both a major health concern and a care-cost issue in the US and the rest of the world. It is estimated that there will be a total of 1,479,350 new cancer cases and 562,340 cancer deaths in 2009 within the US alone. One of the major obstacles in cancer therapy is the ability to target specifically cancer cells. Most existing chemotherapies and
Yi, Lu, Chikezie O, Madu
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Splicing and the Regulation of Viral Gene Expression

1981
Spliced viral mRNA species are synthesized in permissive cells infected by several viruses that possess DNA genomes, such as the parvoviruses, papovaviruses, and adenoviruses, or by those whose life cycle depends on synthesis of a double-stranded DNA copy of an RNA genome, the retroviruses.
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Circadian Regulation of a Viral Gene Promoter in Live Transgenic Mice Expressing Firefly Luciferase

Molecular Imaging and Biology, 2005
This study was conducted to test for possible circadian control of viral infection in live animals using bioluminescence imaging of a firefly luciferase transgene.Transgenic mice expressing the firefly luciferase gene under the control of the promoter and enhancer of the human cytomegalovirus major immediate-early gene (CMV::luc) were examined through ...
Anne M, Collaco   +4 more
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