Results 171 to 180 of about 1,661,421 (342)

Investigation of reversible histone acetylation and dynamics in gene expression regulation using 3D liver spheroid model. [PDF]

Epigenetics Chromatin, 2022
Stransky S, Cutler R, Aguilan J, Nieves E, Sidoli S.   +4 more
europepmc   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Influence of the Bioactive Diet Components on the Gene Expression Regulation. [PDF]

Nutrients, 2021
Mierziak J, Kostyn K, Boba A, Czemplik M, Kulma A, Wojtasik W.   +5 more
europepmc   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Abnormal Gene Expression Regulation Mechanism of Myeloid Cell Nuclear Differentiation Antigen in Lung Adenocarcinoma. [PDF]

Biology (Basel), 2022
Tang Z, Wang L, Bajinka O, Wu G, Tan Y.
europepmc   +1 more source

Regulation of nuclear and mitochondrial gene expression by contractile activity in skeletal muscle.

, 1986
R. Sanders Williams, Stanley Salmons, Eric A. Newsholme, Russel E. Kaufman, Jane Mellor   +4 more
openalex   +1 more source

Posttranscriptional regulation of cellular gene expression by the c-myc oncogene. [PDF]

, 1989
George C. Prendergast, Michael D. Cole
openalex   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation. [PDF]

Cancer Res, 2022
Ladewig E, Michelini F, Jhaveri K, Castel P, Carmona J, Fairchild L, Zuniga AG, Arruabarrena-Aristorena A, Cocco E, Blawski R, Kittane S, Zhang Y, Sallaku M, Baldino L, Hristidis V, Chandarlapaty S, Abdel-Wahab O, Leslie C, Scaltriti M, Toska E.   +19 more
europepmc   +1 more source

Tissue-specific expression and dietary regulation of a chimeric phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic mice.

, 1988
M.M. McGrane, Jerome De Vente, Jeong‐Ho Yun, John W. Bloom, E Park, Anthony Wynshaw‐Boris, Tristan Wagner, Fritz Rottman, Richard W. Hanson   +8 more
openalex   +1 more source