Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
The Nutritional Gene Expression Regulation Potential of a Lysolecithin-Based Product. [PDF]
Curr Issues Mol BiolVan Hoeck V, Spaepen R, Forier B.
europepmc +1 more source
Global Gene Expression Regulation Mediated by TGFβ Through H3K9me3 Mark. [PDF]
Cancer Inform, 2022 Naik A, Dalpatraj N, Thakur N.
europepmc +1 more source
Complementary patterns of even-skipped and fushi tarazu expression involve their differential regulation by a common set of segmentation genes in Drosophila. [PDF]
, 1987 Manfred Frasch, Michael Levine
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ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
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The genetic architecture of gene expression regulation in a <i>Citrus x Poncirus</i> hybrid tolerant to Huanglongbing. [PDF]
Front Plant SciDiaz IA +5 more
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Nutritional compensation of the circadian clock is a conserved process influenced by gene expression regulation and mRNA stability. [PDF]
PLoS Biol, 2023 Kelliher CM +3 more
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Regulation of interleukin 1 gene expression by adherence and lipopolysaccharide. [PDF]
, 1987 Robert C. Fuhlbrigge +3 more
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Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Nuclear functional role of metabolic enzymes and related metabolites: Focus on gene expression regulation. [PDF]
Mol MetabTodisco S +4 more
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