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Osmotic regulation of gene expression
The FASEB Journal, 1996Cells react to increased osmolality with numerous changes in gene expression. The specific genes affected differ between species, but the known osmoprotective effects of the gene products are remarkably similar, particularly with regard to cellular accumulation of compatible organic os‐ molytes. Here we concentrate on the molecular
M B, Burg, E D, Kwon, D, Kültz
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Regulation of Cytokine Gene Expression
Annual Review of Immunology, 1988Following the isolation and characterization of many cytokine genes, we began to understand the mechanisms regulating cytokine gene expression. Needless to say, understanding the mechanisms by which induction of gene expression occurs in a transient, cell type-specific manner in response to extracellular inducers is a central issue in eukaryotic ...
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Regulation Of Neuropeptide Gene Expression
Annual Review of Neuroscience, 1990Understanding of the mechanisms of neuropeptide gene regulation has increased dramatically in the past 5 years. In large part, this increased understanding has resulted from advances in the technology of introducing reporter genes into intact cells in culture.
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Regulating gene expression in gene therapy
Trends in Biotechnology, 1993Ensuring that expression of introduced genes is both safe and effective necessitates directing expression to the appropriate tissue, at levels which produce a therapeutic effect. Extensive research is under way to elucidate the mechanisms and genetic elements involved in regulating expression. With the need to correlate expression levels and phenotypic
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Regulation of opioid gene expression
Peptides, 1983Opioid peptides are synthesized in the form of large precursors, which contain the information for more than one biologically active peptide. Using recombinant DNA technology, three opioid precursors have been sequenced: pro-opiomelanocortin (POMC), proenkephalin and prodynorphin.
O, Civelli +6 more
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Repetitive DNA regulates gene expression
Science, 2023Short tandem repeats affect gene expression by binding regulatory ...
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Regulation of histone gene expression
Current Opinion in Cell Biology, 1992Histone genes are expressed during the S phase of the cell cycle. Control is at multiple levels and is mediated by the integration of regulatory signals in response to cell-cycle progression and the onset of differentiation. Much work has been carried out on the H4 gene promoter, which appears to be organized into a series of distinct regulatory ...
Stein, Gary S. +3 more
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cAMP regulates gastrin gene expression
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1995Gastrin is one of the most potent regulators of acid secretion and gastrointestinal cell growth. A variety of signals regulate gastrin release from the antral G cell. However, whether these secretagogues also stimulate gastrin gene expression has not been established.
A, Shiotani, J L, Merchant
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Regulation of metallothionein gene expression
2000The rapid and robust induction of metallothioneins (MT)-I and II by a variety of inducers that include heavy toxic metals, reactive oxygen species, and different types of stress provide a useful system to study the molecular mechanisms of this unique induction process.
K, Ghoshal, S T, Jacob
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Ploidy Regulation of Gene Expression
Science, 1999Microarray-based gene expression analysis identified genes showing ploidy-dependent expression in isogenic Saccharomyces cerevisiae strains that varied in ploidy from haploid to tetraploid. These genes were induced or repressed in proportion to the number of chromosome sets, regardless of the mating type.
T, Galitski +4 more
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