Results 221 to 230 of about 11,121,866 (385)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Phylogenetic Insights into the Evolutionary History of the <i>RSPO</i> Gene Family in Metazoa. [PDF]

Genes (Basel)
Cheng J, Yang L, Wang S, Luo K, Luo S, Dong Y, Ning Y, Wang W.   +7 more
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Identification and Expression Analysis of Chalcone Synthase Gene Family in Tartary Buckwheat. [PDF]

Genes (Basel)
Wang Q, Jia Y, Lin X, Tan L, Du H, Wang A.   +5 more
europepmc   +1 more source

The Caenorhabditis elegans vitellogenin gene family includes a gene encoding a distantly related protein. [PDF]

, 1985
John Spieth, Thomas Blumenthal
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

An approximately 300 bp deletion involving part of the 5' beta-globin gene region is observed in members of a Turkish family with beta- thalassemia [PDF]

, 1987
JC Diaz-Chico, KG Yang, Abdullah Kutlar, A. L. Reese, M Aksoy, T. H. J. Huisman   +5 more
openalex   +3 more sources

Genome-wide identification and functional analyses of the TCP gene family in Carthamus tinctorius L. [PDF]

Sci Rep
Lu D, Wang L, Yu Y, Li L, Su X, Sun Y, Yang H, Wan X, Li C, Xu L, Yang Q, Tan Z, Liang H.   +12 more
europepmc   +1 more source

Apolipoprotein multigene family: tandem organization of human apolipoprotein AI, CIII, and AIV genes.

, 1985
S K Karathanasis
openalex   +1 more source

Sequence of an expressed human β-tubulin gene containing tenAlufamily members [PDF]

, 1984
Mary Gwo-Shu Lee, Cynthia A. Loomis, Nicholas J. Cowan   +2 more
openalex   +1 more source