Results 21 to 30 of about 13,199,223 (392)

Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. [PDF]

open access: yes, 2016
The unintended consequences of gene targeting in mouse models have not been thoroughly studied and a more systematic analysis is needed to understand the frequency and characteristics of off-target effects.
Adkisson, Michael   +9 more
core   +4 more sources

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools

open access: yesNucleic Acids Res., 2019
The Allele Frequency Net Database (AFND, www.allelefrequencies.net) provides the scientific community with a freely available repository for the storage of frequency data (alleles, genes, haplotypes and genotypes) related to human leukocyte antigens (HLA)
F. González-Galarza   +11 more
semanticscholar   +1 more source

CHD1 Remodels Chromatin and Influences Transient DNA Methylation at the Clock Gene frequency

open access: yesPLoS Genetics, 2011
Circadian-regulated gene expression is predominantly controlled by a transcriptional negative feedback loop, and it is evident that chromatin modifications and chromatin remodeling are integral to this process in eukaryotes. We previously determined that
W. Belden   +4 more
semanticscholar   +1 more source

ANALYSES OF GENE FREQUENCIES [PDF]

open access: yesGenetics, 1973
ABSTRACT Models of variance components and their intraclass correlational equivalences are developed for genes falling into various categories of subdivisions within a population. Estimable functions are elaborated demonstrating that intraclass correlations can be estimated only relative to that for the least related genes in the ...
openaire   +2 more sources

Prevalências das mutações 35delG/GJB2 e del (GJB6-D13S1830) em portadores de surdez não-sindrômica na população do Espírito Santo - Brasil Prevalence of 35delG/GJB2 and del (GJB6-D13S1830) mutations in patients with non-syndromic deafness from a population of Espírito Santo - Brazil

open access: yesBrazilian Journal of Otorhinolaryngology, 2010
Mutações no gene GJB2 constituem a principal causa de surdez genética de herança autossômica recessiva, sendo a mutação 35delG a mais comum em muitos grupos étnicos.
Melissa de Freitas Cordeiro-Silva   +4 more
doaj   +1 more source

Allelic frequency of beta-lactoglobulin gene in different cattle breeds

open access: yesRUDN Journal of Agronomy and Animal Industries, 2023
The results of research on the frequency of genotypes AA, AB, BB and alleles A and B of milk protein beta-lactoglobulin in various cattle breeds over the past decades were presented and summarized.
Natalya A. Khudyakova   +4 more
doaj   +1 more source

Conjugative transfer frequencies of mef(A)-containing Tn1207.3 to macrolide-susceptible Streptococcus pyogenes belonging to different emm types [PDF]

open access: yes, 2014
The aim of this study was to examine the gene transfer potential of mef(A)-containing Tn120.3 to macrolide-susceptible Streptococcus pyogenes belonging to different emm types.
Hadjirin, N. F.   +3 more
core   +1 more source

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer. [PDF]

open access: yes, 2016
A better understanding of the dynamics of molecular changes occurring during the early stages of oral tumorigenesis may help refine prevention and treatment strategies.
Bertolus, Chloé   +14 more
core   +1 more source

Variants of the human PPARG locus and the susceptibility to chronic periodontitis [PDF]

open access: yes, 2011
Apart from its regulatory function in lipid and glucose metabolism, peroxisome proliferator-activated receptor (PPAR)γ has impact on the regulation of inflammation and bone metabolism.
Desvergne B   +5 more
core   +1 more source

Reporte de cuatro casos de pacientes con síndrome de Jarcho-Levin en el departamento de Antioquia, Colombia

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2009
El síndrome de Jarcho-Levin es una displasia esquelética con alteraciones en la morfogénesis vertebral y en la segmentación costal, que se manifiesta con hemivertebras, fusión vertebral o agenesia vertebral, y fusión costal.
Jorge Hernán Montoya   +1 more
doaj   +1 more source

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