Results 221 to 230 of about 1,350,251 (258)
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Rational design of orthogonal libraries of protein coding genes
Proceedings of the ACM Conference on Bioinformatics, Computational Biology and Biomedicine, 2012Array-based oligonucleotide synthesis technologies provide access to thousands of custom-designed sequence variants at low cost. Large-scale synthesis and high-throughput assays have become valuable experimental tools to study in detail the interplay between sequence and function.
Daniel, Ryan, Dimitris, Papamichail
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[The library of Rickettsia prowazekii genes].
Molekuliarnaia genetika, mikrobiologiia i virusologiia, 1987The DNA of Rickettsia provazekii strain E was cleaved by PstI restriction endonuclease under the conditions of partial restriction. The fragments were inserted into the PstI site of pBR325 and cloned in this plasmid. E. coli strain HB101 was used as a recipient for cloning.
M I, Artem'ev +2 more
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Selection of Recombinant Antibodies from Antibody Gene Libraries
2013Antibodies are indispensable detection reagents for research and diagnostics and represent the biggest class of biological therapeutics on the market. In vitro antibody selection systems offer many advantages over animal-based technologies because the whole selection process is independent of the in vivo immune response.
Michael, Hust +3 more
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Reporter Gene Assays Using Transfectable Functional Genomics Libraries
2018Transfectable functional genomics libraries are traditionally the workhorses of functional genomics screening using reporter gene assays. These libraries offer insight into fundamental cellular processes governing health and disease and can be utilized in an arrayed fashion which makes them uniquely suited to deconvolute complicated disease phenotypes ...
Genevieve, Welch +2 more
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Reporter Gene Assays Using Viral Functional Genomics Libraries
2018While transfectable libraries are the workhorse for many screening cores, there is one obvious area where these reagents are not useful-hard to transfect cell lines and primary cells. One solution to this problem is the use of virus to introduce genomic reagents.
Genevieve, Welch +2 more
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The Yale Human Gene Mapping Library
Cytogenetic and Genome Research, 1984R L, Miller +3 more
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Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
exaly