Results 21 to 30 of about 1,329,302 (305)
Synthetic and Systems Biotechnology, 2017 Engineering cell factories for producing biofuels and pharmaceuticals has spurred great interests to develop rapid and efficient synthetic biology tools customized for modular pathway engineering.
Erqing Jin +5 more
doaj +1 more source
Modifications at the C-Terminus To Improve Pyrrole−Imidazole Polyamide Activity in Cell Culture [PDF]
, 2009 Pyrrole−imidazole (Py-Im) hairpin polyamides are a class of small molecule DNA minor groove binding compounds that have been shown to modulate endogenous gene expression in cell culture.
Dervan, Peter B., Jacobs, Claire S.
core +2 more sources
Mutant non-coding RNA resource in mouse embryonic stem cells
Disease Models & Mechanisms, 2021 Gene trapping is a high-throughput approach that has been used to introduce insertional mutations into the genome of mouse embryonic stem (ES) cells. It is performed with generic gene trap vectors that simultaneously mutate and report the expression of ...
Jens Hansen +2 more
doaj +1 more source
Isolation of pigment cell specific genes in the sea urchin embryo by differential macroarray screening [PDF]
, 2003 New secondary mesenchyme specific genes, expressed exclusively in pigment cells, were isolated from sea urchin embryos using a differential screening of a macroarray cDNA library. The comparison was performed between mRNA populations of embryos having an
Calestani, Cristina +2 more
core +1 more source
ERgene: Python library for screening endogenous reference genes [PDF]
Scientific Reports, 2020 AbstractIn gene expression analysis, sample differences and experimental operation differences are common, but sometimes, these differences will cause serious errors to the results or even make the results meaningless. Finding suitable internal reference genes efficiently to eliminate errors is a challenge.
Zeng, Zehua +3 more
openaire +2 more sources
Cloning of a Transglutaminase Gene from an Indonesian Streptomyces Strain
Squalen, 2016 Microbial Transglutaminase (MTGase, EC 2.3.2.13) is an enzyme that catalyzes the transfer of acyl group. Many microbial strains that produce MTGase belong to Streptomyces members. This research was aimed at cloning of a MTGase gene.
Seprianto Chaniago
doaj +1 more source
The COVID-19 Gene and Drug Set Library [PDF]
SSRN Electronic Journal, 2020 Abstract The coronavirus (CoV) severe acute respiratory syndrome (SARS)-CoV-2 (COVID-19) pandemic has received rapid response by the research community to offer suggestions for repurposing of approved drugs as well as to improve our understanding of the COVID-19 viral life cycle molecular mechanisms.
Maxim V. Kuleshov +9 more
openaire +3 more sources
Microbial population changes during bioremediation of nitroaromatic - and nitramine-contaminated lagoon [PDF]
, 2008 Nitration reactions of aromatic compounds are commonly involved in military industrial processes. Military industries treated their process effluents using lagoon systems for many years.
Goñi, Marisol +5 more
core +1 more source
On the utility of RNA sample pooling to optimize cost and statistical power in RNA sequencing experiments [PDF]
, 2020 Background: In gene expression studies, RNA sample pooling is sometimes considered because of budget constraints or lack of sufficient input material. Using microarray technology, RNA sample pooling strategies have been reported to optimize both the cost
Assefa, Alemu Takele +2 more
core +2 more sources
Screening technology of cyclic peptide library based on gene encoding
Medicine in Drug Discovery, 2022 As a powerful tool for the discovery of peptide compounds, high-throughput library screening technology can also perform multitarget screening with high chemical diversity as a condition, which accelerates the process of exploring high-affinity peptide ...
Yangqiang Chen +5 more
doaj +1 more source