Results 51 to 60 of about 1,350,251 (258)

RNA modulators of complex phenotypes in mammalian cells. [PDF]

open access: yesPLoS ONE, 2009
RNA-mediated gene silencing, in the form of RNA interference (RNAi) or microRNAs (miRNAs) has provided novel tools for gene discovery and validation in mammalian cells.
Angela Lai   +5 more
doaj   +1 more source

Generation and analysis of expressed sequence tags from Botrytis cinerea [PDF]

open access: yes, 2006
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000200018&lng=es&nrm=isoBotrytis cinerea is a filamentous plant pathogen of a wide range of plant species, and its infection may cause enormous damage both during plant growth and in ...
Holmes, David   +4 more
core   +2 more sources

Tail-tape-fused virion and non-virion RNA polymerases of a thermophilic virus with an extremely long tail

open access: yesNature Communications
Thermus thermophilus bacteriophage P23-45 encodes a giant 5,002-residue tail tape measure protein (TMP) that defines the length of its extraordinarily long tail.
Anastasiia Chaban   +15 more
doaj   +1 more source

Randomly barcoded transposon mutant libraries for gut commensals I: Strategies for efficient library construction

open access: yesCell Reports
Summary: Randomly barcoded transposon mutant libraries are powerful tools for studying gene function and organization, assessing gene essentiality and pathways, discovering potential therapeutic targets, and understanding the physiology of gut bacteria ...
Surya Tripathi   +17 more
doaj   +1 more source

A new approach to understanding T cell development: the isolation and characterization of immature CD4-, CD8-, CD3- T cell cDNAs by subtraction cloning [PDF]

open access: yes, 1992
During T cell development in the mammalian thymus, immature T cells are observed that lack the cell surface markers CD4, CD8, and CD3. A subtracted cDNA library was constructed to isolate cDNAs that are specific for these immature T cells.
Gese, Elaine, Hood, Leroy, Orr, Sally L.
core  

gene library

open access: yes, 2014
Citation: 'gene library' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.G02606 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Gene Expression From Random Libraries of Yeast Promoters [PDF]

open access: yesGenetics, 2006
Abstract Genomewide techniques to assay gene expression and transcription factor binding are in widespread use, but are far from providing predictive rules for the function of regulatory DNA. To investigate more intensively the grammar rules for active regulatory sequence, we made libraries from random ligations of a very restricted set ...
Martin, Ligr   +3 more
openaire   +2 more sources

Gene and library synthesis without amplification: polymerase step reaction (PSR)

open access: yesBioTechniques, 2015
Current gene synthesis methods often incorporate a PCR amplification step in order to yield final material sufficient for resolution from multiple off-products. These amplification steps can cause stochastic sampling effects that propagate errors in gene
Zhuo-Bin Lee   +3 more
doaj   +1 more source

Identification of Sequences Encoding Symbiodinium minutum Mitochondrial Proteins. [PDF]

open access: yes, 2016
The dinoflagellates are an extremely diverse group of algae closely related to the Apicomplexa and the ciliates. Much work has previously been undertaken to determine the presence of various biochemical pathways within dinoflagellate mitochondria ...
Butterfield, Erin R.   +2 more
core   +4 more sources

GOATOOLS: A Python library for Gene Ontology analyses [PDF]

open access: yesScientific Reports, 2018
AbstractThe biological interpretation of gene lists with interesting shared properties, such as up- or down-regulation in a particular experiment, is typically accomplished using gene ontology enrichment analysis tools. Given a list of genes, a gene ontology (GO) enrichment analysis may return hundreds of statistically significant GO results in a “flat”
D. V. Klopfenstein   +13 more
openaire   +6 more sources

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