Results 71 to 80 of about 806,287 (306)

Interview with Gene Huguelet

, 2006
Gene Huguelet, retired Director of Library Services at UNCW's Randall Library from 1977 to 1996, shares professional reminiscences which include the formation of the Coastal Library Consortium and the automation and expansion of Randall Library.
Huguelet, Gene
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Construction of the suppression subtractive cDNA libraries of human large cell lung cancer line L9981 before and after transfection with nm23-H1 gene

Chinese Journal of Lung Cancer, 2008
Background and objective It has been proven that nm23-H1 gene is an important metastatic-suppressed gene of lung cancer. In order to screen the differential expression genes related to nm23-H1, we constructed the suppression subtractive cDNA libraries of
Sujuan YE, Zhihua FENG, Wen ZHU, Chunji CAI, Lu LI, Liya SUN, Haisu WAN, Li MA, Qinghua ZHOU   +8 more
doaj  

Randomly barcoded transposon mutant libraries for gut commensals I: Strategies for efficient library construction

Cell Reports
Summary: Randomly barcoded transposon mutant libraries are powerful tools for studying gene function and organization, assessing gene essentiality and pathways, discovering potential therapeutic targets, and understanding the physiology of gut bacteria ...
Surya Tripathi, Carlos Geert Pieter Voogdt, Stefan Oliver Bassler, Mary Anderson, Po-Hsun Huang, Nazgul Sakenova, Tümay Capraz, Sunit Jain, Alexandra Koumoutsi, Afonso Martins Bravo, Valentine Trotter, Michael Zimmerman, Justin L. Sonnenburg, Cullen Buie, Athanasios Typas, Adam M. Deutschbauer, Anthony L. Shiver, Kerwyn Casey Huang   +17 more
doaj   +1 more source

Other Title: Gene Alexander Howe

, 2013
Compiled in book form 2013 by staff of the State Library of Kansas.
Kansas State Library. State Documents Section.
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Chromosome-segment scanning for gain- or loss-of-function screening (CHASING)

iScience
Summary: Identifying beneficial or functional mutations for a specific species is a task always relies on the labor-intensive construction of a library containing thousands of single-gene knockout or interference strains.
Yan Xia, Lichao Sun, Zeyu Liang, Zhongrao Han, Jing Li, Pengyu Dong, Yi-Xin Huo, Shuyuan Guo   +7 more
doaj   +1 more source

Creating a RAW264.7 CRISPR-Cas9 Genome Wide Library

Bio-Protocol, 2017
The bacterial clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 genome editing tools are used in mammalian cells to knock-out specific genes of interest to elucidate gene function.
Brooke Napier , Denise Monack
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Robert Neufeld, Library Director, groundbreaking ceremony for the Roseland Free Public Library, Roseland, N.J., November 17, 1985

, 1985
The Director rejoices. Library Director, Robert Neufeld, gives his speech to the guests of the Groundbreaking Ceremony at the new library site, 20 Roseland Avenue, Roseland, NJ, on Sunday, November 17 ...

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