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Repeated MDA5 Gene Loss in Birds: An Evolutionary Perspective [PDF]
Viruses, 2021 Two key cytosolic receptors belonging to the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) family sense the viral RNA-derived danger signals: RIG-I and melanoma differentiation-associated protein 5 (MDA5).
Veronika Krchlíková +6 more
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Evolutionary differences in gene loss and pseudogenization among mycoheterotrophic orchids in the tribe Vanilleae (subfamily Vanilloideae) [PDF]
Frontiers in Plant Science, 2023 IntroductionGaleola lindleyana is a mycoheterotrophic orchid belonging to the tribe Vanilleae within the subfamily Vanilloideae.MethodsIn this study, the G.
Lisi Zhou +4 more
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Frontiers in Cell and Developmental Biology, 2021 Gene loss is a pervasive source of genetic variation that influences species evolvability, biodiversity and the innovation of evolutionary adaptations. To better understand the evolutionary patterns and impact of gene loss, here we investigate as a case ...
Josep Martí-Solans +6 more
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Genome-wide identification and characterization of toll-like receptor 5 (TLR5) in fishes
Frontiers in Genetics, 2023 Toll-like receptors 5 (TLR5), a member of the toll-like receptors (TLRs) family, is a class of pattern recognition receptors (PRRs) that recognize pathogen-associated molecular patterns (PAMPs).
Kai Zhang +10 more
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Lost in the bloom: DNA-PKcs in green plants
Frontiers in Plant Science, 2023 The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a protein encoded by the PRKDC gene in humans and plays a crucial role in repairing DNA double-strand breaks (DSBs).
Koppolu Raja Rajesh Kumar
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The impact of local genomic properties on the evolutionary fate of genes
eLife, 2023 Functionally indispensable genes are likely to be retained and otherwise to be lost during evolution. This evolutionary fate of a gene can also be affected by factors independent of gene dispensability, including the mutability of genomic positions, but ...
Yuichiro Hara, Shigehiro Kuraku
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Frontiers in Genetics, 2020 We take advantage of synteny blocks, the analytical construct enabled at the evolutionary moment of speciation or polyploidization, to follow the independent loss of duplicate genes in two sister species or the loss through fractionation of syntenic ...
Zhe Yu +3 more
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Frontiers in Plant Science, 2022 MADS-box is an important transcription factor family that is involved in the regulation of various stages of plant growth and development, especially flowering regulation and flower development.
Kunyu Duan +8 more
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The life cycle of Drosophila orphan genes
eLife, 2014 Orphans are genes restricted to a single phylogenetic lineage and emerge at high rates. While this predicts an accumulation of genes, the gene number has remained remarkably constant through evolution. This paradox has not yet been resolved.
Nicola Palmieri +2 more
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Extinction of tyrosine aminotransferase gene activity in somatic cell hybrids involves modification and loss of several essential transcription factors [PDF]
, 1993 Extinction is defined as the loss of cell type-specific gene expression that occurs in somatic cell hybrids derived by fusion of cells with dissimilar phenotypes.
Boshart, Michael +2 more
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