Results 71 to 80 of about 2,855,271 (302)

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Efficient CRISPR-rAAV engineering of endogenous genes to study protein function by allele-specific RNAi. [PDF]

, 2015
Gene knockout strategies, RNAi and rescue experiments are all employed to study mammalian gene function. However, the disadvantages of these approaches include: loss of function adaptation, reduced viability and gene overexpression that rarely matches ...
Dowdy, Steven F, Kaulich, Manuel, Lee, Yeon J, Lönn, Peter, Meade, Bryan R, Springer, Aaron D   +5 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Advances in genetic hearing loss: CIB2 gene [PDF]

European Archives of Oto-Rhino-Laryngology, 2016
Hearing plays a crucial role in human development. Receiving and processing sounds are essential for the advancement of the speech ability during the early childhood and for a proper functioning in the society. Hearing loss is one of the most frequent disabilities that affect human senses. It can be caused by genetic or environmental factors or both of
Agnieszka Jacoszek, Agnieszka Pollak, Rafał Płoski, Monika Ołdak   +3 more
openaire   +2 more sources

Genomic Variability of Monkeypox Virus among Humans, Democratic Republic of the Congo

Emerging Infectious Diseases, 2014
Monkeypox virus is a zoonotic virus endemic to Central Africa. Although active disease surveillance has assessed monkeypox disease prevalence and geographic range, information about virus diversity is lacking.
Jeffrey R. Kugelman, Sara C. Johnston, Prime M. Mulembakani, Neville Kisalu, Michael S. Lee, Galina Koroleva, Sarah E. McCarthy, Marie C. Gestole, Nathan D. Wolfe, Joseph N. Fair, Bradley S. Schneider, Linda L. Wright, John Huggins, Chris A. Whitehouse, Emile Okitolonda Wemakoy, Jean Jacques Muyembe-Tamfum, Lisa E. Hensley, Gustavo F. Palacios, Anne W. Rimoin   +18 more
doaj   +1 more source

Potential allopolyploid origin of Ericales revealed with gene-tree reconciliation

Frontiers in Plant Science, 2022
Few incidents of ancient allopolyploidization (polyploidization by hybridization or merging diverged genomes) were previously revealed, although there is significant evidence for the accumulation of whole genome duplications (WGD) in plants.
Shuai Nie, Xue-Chan Tian, Lei Kong, Shi-Wei Zhao, Zhao-Yang Chen, Si-Qian Jiao, Si-Qian Jiao, Yousry A. El-Kassaby, Ilga Porth, Fu-Sheng Yang, Fu-Sheng Yang, Fu-Sheng Yang, Wei Zhao, Jian-Feng Mao   +13 more
doaj   +1 more source

An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors. [PDF]

, 2009
To address the biological heterogeneity of lung cancer, we studied 199 lung adenocarcinomas by integrating genome-wide data on copy number alterations and gene expression with full annotation for major known somatic mutations in this cancer.
Brennan, C, Broderick, S, Chitale, D, Gerald, W, Golas, B, Gong, Y, Ladanyi, M, Major, J, Motoi, N, Pao, W, Reinersman, J, Rusch, V, Sander, C, Seshan, V, Somwar, R, Szoke, J, Taylor, Barry, Wang, L, Zakowski, M   +18 more
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

The ecological adaptation of the unparalleled plastome character evolution in slipper orchids

Frontiers in Plant Science, 2022
Plastomes may have undergone adaptive evolution in the process of plant adaptation to diverse environments, whereby species may differ in plastome characters.
Chao Hu, Chao Hu, Chao Hu, Zhenbin Jiao, Zhenbin Jiao, Xinyan Deng, Xiongde Tu, Aixian Lu, Aixian Lu, Chengzhi Xie, Kai Jiang, Xinhua Zeng, Zhong-Jian Liu, Weichang Huang, Yibo Luo, Yibo Luo   +15 more
doaj   +1 more source

The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma

, 2016
The REL gene, encoding the NF-κB subunit c-Rel, is frequently amplified in B-cell lymphoma and functions as a tumour-promoting transcription factor. Here we report the surprising result that c-rel–/– mice display significantly earlier lymphomagenesis in ...
Bacon, C.M., Butterworth, J.A., Campbell, K.J., Cockell, S.J., Gewurz, B.E., Hunter, J.E., Perkins, N.D., Sellier, H., Thomas, H.D., Zhao, B.   +9 more
core   +1 more source