Results 21 to 30 of about 169 (169)

Expansion of the Gene Ontology knowledgebase and resources [PDF]

Nucleic Acids Research, 2016
The Gene Ontology (GO) is a comprehensive resource of computable knowledge regarding the functions of genes and gene products. As such, it is extensively used by the biomedical research community for the analysis of -omics and related data. Our continued focus is on improving the quality and utility of the GO resources, and we welcome and encourage ...
Antonazzo, G, Attrill, H, Brown, NH, Marygold, SJ, McQuilton, P, Ponting, L, Millburn, GH, Rey, AJ, Stefancsik, R, Tweedie, S, Harris, MA, Hayles, J, Oliver, SG, Rutherford, K, Wood, V   +14 more
openaire   +9 more sources

The Gene Ontology of eukaryotic cilia and flagella [PDF]

Cilia, 2017
Recent research into ciliary structure and function provides important insights into inherited diseases termed ciliopathies and other cilia-related disorders. This wealth of knowledge needs to be translated into a computational representation to be fully exploitable by the research community.
Jane Lomax, Toby J. Gibson, Grischa Toedt, Paola Roncaglia, Lora Nacheva, Rachael P. Huntley, Rachael P. Huntley, Teunis J. P. van Dam, Teunis J. P. van Dam, Martijn A. Huynen, Karen R. Christie   +10 more
openaire   +10 more sources

A Gene Ontology Tutorial in Python [PDF]

, 2016
This chapter is a tutorial on using Gene Ontology resources in the Python programming language. This entails querying the Gene Ontology graph, retrieving Gene Ontology annotations, performing gene enrichment analyses, and computing basic semantic similarity between GO terms.
Christophe Dessimoz, Christophe Dessimoz, Christophe Dessimoz, Alex Warwick Vesztrocy, Alex Warwick Vesztrocy   +4 more
openaire   +4 more sources

The Neural/Immune Gene Ontology: clipping the Gene Ontology for neurological and immunological systems [PDF]

BMC Bioinformatics, 2010
Abstract Background The Gene Ontology (GO) is used to describe genes and gene products from many organisms. When used for functional annotation of microarray data, GO is often slimmed by editing so that only higher level terms remain.
Alon Monsonego, Eitan Rubin, Nophar Geifman   +2 more
openaire   +4 more sources

Formalization of gene regulation knowledge using ontologies and gene ontology causal activity models

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2021
Gene regulation computational research requires handling and integrating large amounts of heterogeneous data. The Gene Ontology has demonstrated that ontologies play a fundamental role in biological data interoperability and integration. Ontologies help to express data and knowledge in a machine processable way, which enables complex querying and ...
Cortés, BJ, Vera-Ramos, JA, Lovering, RC, Gaudet, P, Laegreid, A, Logie, C, Schulz, S, Del Mar Roldán-García, M, Kuiper, M, Fernández-Breis, JT   +9 more
openaire   +8 more sources

From Plant Ontology to Gene Ontology and back

Current Plant Biology, 2018
Our recent goal for the Plant Ontology (PO) is to have it integrated with the Gene Ontology (GO). The simplest aspect of this is to link morphological and anatomical images of structures for PO terms with genes involved in the development of those structures (GO terms).
Cecilia Zumajo-Cardona, Cecilia Zumajo-Cardona, Dennis W. Stevenson   +2 more
openaire   +4 more sources

Logical Gene Ontology Annotations (GOAL): exploring gene ontology annotations with OWL [PDF]

Journal of Biomedical Semantics, 2012
Ontologies such as the Gene Ontology (GO) and their use in annotations make cross species comparisons of genes possible, along with a wide range of other analytical activities. The bio-ontologies community, in particular the Open Biomedical Ontologies (OBO) community, have provided many other ontologies and an increasingly large volume of annotations ...
Jupp, Simon, Stevens, Robert, Hoehndorf, Robert   +2 more
openaire   +5 more sources

Improvements to cardiovascular Gene Ontology

Atherosclerosis, 2009
Gene Ontology (GO) provides a controlled vocabulary to describe the attributes of genes and gene products in any organism. Although one might initially wonder what relevance a 'controlled vocabulary' might have for cardiovascular science, such a resource is proving highly useful for researchers investigating complex cardiovascular disease phenotypes as
Ruth C. Lovering, Emily Dimmer, Philippa J. Talmud   +2 more
openaire   +3 more sources

The Gene Ontology in 2010: extensions and refinements [PDF]

Nucleic Acids Research, 2009
The Gene Ontology (GO) Consortium (http://www.geneontology.org) (GOC) continues to develop, maintain and use a set of structured, controlled vocabularies for the annotation of genes, gene products and sequences. The GO ontologies are expanding both in content and in structure.
BERARDINI TZ, LI D, HUALA E, BRIDGES S, BURGESS S, MCCARTHY F, CARBON S, LEWIS SE, MUNGALL CJ, ABDULLA A, WOOD V, FELTRIN E, VALLE, GIORGIO, CHISHOLM RL, FEY P, GAUDET P, KIBBE W, BASU S, BUSHMANOVA Y, EILBECK K, SIEGELE DA, MCINTOSH B, RENFRO D, ZWEIFEL A, HU JC, ASHBURNER M, TWEEDIE S, ALAM FARUQUE Y, APWEILER R, AUCHINCHLOSS A, BAIROCH A, BARRELL D, BINNS D, BLATTER MC, BOUGUELERET L, BOUTET E, BREUZA L, BRIDGE A, BROWNE P, CHAN WM, COUDERT E, DAUGHERTY L, DIMMER E, EBERHARDT R, ESTREICHER A, FAMIGLIETTI L, FERRO ROJAS S, FEUERMANN M, FOULGER R, GRUAZ GUMOWSKI N, HINZ U, HUNTLEY R, JIMENEZ S, JUNGO F, KELLER G, LAIHO K, LEGGE D, LEMERCIER P, LIEBERHERR D, MAGRANE M, O'DONOVAN C, PEDRUZZI I, POUX S, RIVOIRE C, ROECHERT B, SAWFORD T, SCHNEIDER M, STANLEY E, STUTZ A, SUNDARAM S, TOGNOLLI M, XENARIOS I, HARRIS MA, DEEGAN JI, IRELAND A, LOMAX J, JAISWAL P, CHIBUCOS M, GIGLIO MG, WORTMAN J, HANNICK L, MADUPU R, BOTSTEIN D, DOLINSKI K, LIVSTONE MS, OUGHTRED R, BLAKE JA, BULT C, DIEHL AD, DOLAN M, DRABKIN H, EPPIG JT, HILL DP, NI L, RINGWALD M, SITNIKOV D, COLLMER C, TORTO ALALIBO T, LAULEDERKIND S, SHIMOYAMA M, TWIGGER S, D'EUSTACHIO P, MATTHEWS L, BALAKRISHNAN R, BINKLEY G, CHERRY JM, CHRISTIE KR, COSTANZO MC, ENGEL SR, FISK DG, HIRSCHMAN JE, HITZ BC, HONG EL, KRIEGER CJ, MIYASATO SR, NASH RS, PARK J, SKRZYPEK MS, WENG S, WONG ED, ASLETT M, CHAN J, KISHORE R, STERNBERG P, VAN AUKE K, KHODIYAR VK, LOVERING RC, TALMUD PJ, HOWE D, WESTERFIELD M.   +129 more
openaire   +5 more sources

The Gene Ontology Handbook [PDF]

, 2017
#TheGeneOntologyHandbook ; #BiologicalKnowledge ; This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made ...
Dessimoz, Christophe, Škunca, Nives
openaire   +3 more sources