Results 91 to 100 of about 9,406 (131)

Enhanced strand transfer and mismatch extension by HIV-1C reverse transcriptase promote sequence motif duplication. [PDF]

J Virol
Panchapakesan A, Joshi AP, Amanullah A, Pargain N, Mehta K, Shanmugam M, Singh J, Saini C, Nala N, Ramagopal UA, Ranga U.   +10 more
europepmc   +1 more source

The role of Nef in the long-term persistence of the replication-competent HIV reservoir in South African women. [PDF]

J Virol
Ismail SD, Sebaa S, Abrahams B, Nason MC, Mumby MJ, Dikeakos JD, Joseph SB, Moeser M, Swanstrom R, Garrett N, Williamson C, Quinn TC, Abrahams M-R, Redd AD.   +13 more
europepmc   +1 more source

M-Sec promotes the production of infectious HIV-1 virus through the exocyst complex in macrophages. [PDF]

PLoS Pathog
Mahmoud RM, Hiyoshi M, Abdelnaser RA, Monde K, Monde N, Koma T, Mizuno H, Habash SA, Takahashi N, Maeda Y, Ono A, Suzu S.   +11 more
europepmc   +1 more source

Functional association between the nef gene product and gag-pol region of HIV-1.

Functional association between the nef gene product and gag-pol region of HIV-1.
openaire  

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. [PDF]

Journal of Experimental Medicine, 1994
Considerable controversy and uncertainty have surrounded the biological function of the Human Immunodeficiency Virus (HIV)-1 nef gene product. Initial studies suggested that this early, nonstructural viral protein functioned as a negative regulatory factor; thus, it was proposed to play a role in establishing or maintaining viral latency.
Michael D Miller, Greene W C
exaly   +5 more sources

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Specificity of anti-Nef antibodies produced in mice immunized with DNA encoding the HIV-1 nef gene product

Vaccine, 1999
Mice immunized with plasmid DNA encoding Nef regulatory protein of human immunodeficiency virus type 1 developed high levels of anti-Nef antibodies. After 4 intramuscular injections of 100 microg plasmid DNA, anti-Nef antibodies reached titers up to 2 x 10(4). A significant specific antibody response was maintained for at least 16 months.
Luc Montagnier, Elmostafa Bahraoui, L Montagnier   +2 more
exaly   +3 more sources

Functional association between thenefgene product andgag-polregion of HIV-1

FEBS Letters, 2000
Yasumasa Iwatani, A Ishimoto
exaly   +2 more sources

Biochemical and biological comparison of HIV-1 NEF and ras gene products

Virology, 1991
Human immunodeficiency virus type 1 (HIV-1) NEF protein has been reported to share certain biochemical and structural properties with known oncoproteins like src or rats. To determine whether this is a general property of NEF from various HIV isolates, three different NEF proteins were expressed in Escherichia coli using a thermoinducible expression ...
A R, Nebreda, T, Bryan, F, Segade, P, Wingfield, S, Venkatesan, E, Santos   +5 more
openaire   +2 more sources

The HIV-1 nef gene product is associated with phosphorylation of a 46 kD cellular protein

AIDS, 1992
To study the biochemical properties of the HIV-1 nef gene product.Earlier reports suggested that Nef protein is phosphorylated and has kinase activity. These properties were examined using an in vitro translated product.A DNA fragment encoding Nef of HIV-1SF2 was transcribed in vitro under the control of T7 promoter.
L, Poulin, J A, Levy
openaire   +2 more sources