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THE 27 KD PROTEIN ENCODED BY THE HIV NEF GENE SHARES STRUCTURAL AND FUNCTIONAL HOMOLOGIES WITH SEVERAL ONCOGENE PRODUCTS

1991
The HIV genome contains nine coding regions, whose function in viral replication is still partially unknown. One of these, nef (Negative factor, previously called 3'-orf or orf-B), encodes a 27 kilodalton protein (p27nef) inducing an early specific immune response in infected patients. p27nef resembles an oncogene product: (a) it is myristylated on the
GALIMI F   +2 more
openaire   +2 more sources

The HIV-1 nef gene product

Biochemical Society Transactions, 1992
M, Harris   +3 more
openaire   +2 more sources

Production of Doughnut-Shaped, Protease-Defective Particles from a Human T Cell Clone Carrying a Provirus with Specific Mutations in the env, pol, vpr , and nef Genes

AIDS Research and Human Retroviruses, 1997
M K, Bahmani   +11 more
openaire   +2 more sources

Effects of HIV-1 nef on cellular gene expression profiles

Journal of Biomedical Science, 2002
Jeffrey Trent   +2 more
exaly  

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