Results 1 to 10 of about 6,798,395 (302)

Successful treatment of a pure red-cell aplasia patient with γδT cells and clonal TCR gene rearrangement: A case report [PDF]

Frontiers in Immunology, 2023
Pure red-cell aplasia (PRCA) is a syndrome associated with reduced erythroid precursors. This report presents the case of an elderly PRCA patient with significantly proliferated γδT cells and clonal T-cell receptor (TCR) gene rearrangement.
Xian Li, Xinyi Zhu, Xiaohong Zhang, Weiqin Wang   +3 more
doaj   +2 more sources

Prevalence of Gene Rearrangement by Multiplex PCR in De Novo Acute Myeloid Leukemia in Adult Iraqi Patients [PDF]

Journal of Blood Medicine, 2023
Ali AlJabban, Jaffar Alalsaidissa Department of Pathology, College of Medicine, University of Baghdad, Baghdad, IraqCorrespondence: Ali AlJabban, Department of Pathology, College of medicine, University of Baghdad, Baghdad, Iraq, Tel +9647706056226 ...
AlJabban A, Alalsaidissa J
doaj   +2 more sources

Hidden breakpoints in genome alignments [PDF]

WABI 2012, LNBI 7534:391-403 (2012), 2012
During the course of evolution, an organism's genome can undergo changes that affect the large-scale structure of the genome. These changes include gene gain, loss, duplication, chromosome fusion, fission, and rearrangement. When gene gain and loss occurs in addition to other types of rearrangement, breakpoints of rearrangement can exist that are only ...
A. Rambaut, A.C.E. Darling, A.E. Darling, A.L. Delcher, C.D. Greenman, D. Medini, E. Tannier, G. Fudenberg, M. Blanchette, M. Nowacki, M.A. Umbarger, S. De, S. Schwartz, S.V. Angiuoli, V. Kolmogorov   +14 more
arxiv   +3 more sources

Impact of observational incompleteness on the structural properties of protein interaction networks [PDF]

, 2006
The observed structure of protein interaction networks is corrupted by many false positive/negative links. This observational incompleteness is abstracted as random link removal and a specific, experimentally motivated (spoke) link rearrangement. Their impact on the structural properties of gene-duplication-and-mutation network models is studied.
Albert, Alfarano, Bader, Bader, Berg, Breitkreutz, Dall’Asta, Deane, Eisenberg, Gavin, Ho, Ingmar Glauche, Ispolatov, Ispolatov, Lee, Martin Greiner, Mathias Kuhnt, Mering, Milo, Newman, Przulj, Salwinski, Scholz, Sole, Tong, Vazquez, Vazquez, Zanzoni, Ziv   +28 more
arxiv   +3 more sources

Gene conversion in human rearranged immunoglobulin genes [PDF]

Immunogenetics, 2006
Over the past 20 years, many DNA sequences have been published suggesting that all or part of the V(H) segment of a rearranged immunoglobulin gene may be replaced in vivo. Two different mechanisms appear to be operating. One of these is very similar to primary V(D)J recombination, involving the RAG proteins acting upon recombination signal sequences ...
John M Darlow, David I. Stott
openaire   +6 more sources

Progressive Mauve: Multiple alignment of genomes with gene flux and rearrangement [PDF]

arXiv, 2009
Multiple genome alignment remains a challenging problem. Effects of recombination including rearrangement, segmental duplication, gain, and loss can create a mosaic pattern of homology even among closely related organisms. We describe a method to align two or more genomes that have undergone large-scale recombination, particularly genomes that have ...
Darling, Aaron E., Mau, Bob, Perna, Nicole T.   +2 more
arxiv   +3 more sources

Gene rearrangements and translocations in lymphoproliferative diseases [PDF]

Blood, 1989
On discute les reorganisations a genes des immunoglobulines (Ig) et des recepteurs des cellules T (RCT) dans les affections lymphoproliferatives. La complexite des types de reorganisation peut refleter une population de cellules clonees provenant d'une cellule hematopoietique indifferenciee qui est capable de reorganisation de ces genes avant l ...
H Griesser, D Tkachuk, MD Reis, TW Mak
openalex   +4 more sources

The zero exemplar distance problem [PDF]

, 2010
Given two genomes with duplicate genes, \textsc{Zero Exemplar Distance} is the problem of deciding whether the two genomes can be reduced to the same genome without duplicate genes by deleting all but one copy of each gene in each genome. Blin, Fertin, Sikora, and Vialette recently proved that \textsc{Zero Exemplar Distance} for monochromosomal genomes
D. Sankoff, G. Blin, J.E. Hopcroft, M.R. Garey, P. Bonizzoni, R.G. Downey, S. Angibaud, S.S. Adi, V. Ferretti, Z. Chen, Z. Chen   +10 more
arxiv   +4 more sources

Comparative Analysis of Complete Mitochondrial Genome of Ariosoma meeki (Jordan and Snider, 1900), Revealing Gene Rearrangement and the Phylogenetic Relationships of Anguilliformes [PDF]

Biology, 2023
The mitochondrial genome structure of a teleostean group is generally considered to be conservative. However, two types of gene arrangements have been identified in the mitogenomes of Anguilliformes.
Youkun Huang, Kehua Zhu, Yawei Yang, Liancheng Fang, Zhaowen Liu, Jia Ye, Caiyi Jia, Jianbin Chen, Hui Jiang   +8 more
doaj   +2 more sources

Comparative Mitogenomic Analyses of Hydropsychidae Revealing the Novel Rearrangement of Protein-Coding Gene and tRNA (Trichoptera: Annulipalpia)

Insects, 2022
Gene rearrangement of the mitochondrial genome of insects, especially the rearrangement of protein-coding genes, has long been a hot topic for entomologists.
Xinyu Ge, Haoming Zang, Xiaoyun Ye, Lang Peng, Beixin Wang, Gang Lian, Changhai Sun   +6 more
doaj   +1 more source