Results 11 to 20 of about 6,798,395 (302)
Insects, 2022 (1) Background: Gene rearrangement of mitochondrial genome, especially those with phylogenetic signals, has long fascinated evolutionary biologists. The synapomorphic gene rearrangements have been identified across multiple orders and at many different ...
Chen-Guang Zheng +6 more
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Mechanics of T cell receptor gene rearrangement [PDF]
Current Opinion in Immunology, 2009 The four T cell receptor genes (Tcra, Tcrb, Tcrg, Tcrd) are assembled by V(D)J recombination according to distinct programs during intrathymic T cell development. These programs depend on genetic factors, including gene segment order and recombination signal sequences. They also depend on epigenetic factors.
M. Krangel
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Rearranging Detection of Gene Rearrangements [PDF]
Journal of Thoracic Oncology, 2015 ®ecent years have witnessed a dramatic expansion in our knowledge of the genetic diversity of non–small-cell lung cancer (NSCLC), and in particular adenocarcinoma. This appreciation of the genetic landscape of the disease has resulted in the development of targeted therapies that are directed to ward activated oncogenes.
Dara L. Aisner +2 more
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Insects, 2022 Extensive gene rearrangement is characteristic in the mitogenomes of thrips (Thysanoptera), but the historical process giving rise to the contemporary gene rearrangement pattern remains unclear.
Qiaoqiao Liu +5 more
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Definitions, 2020 Any DNA sequence rearrangement that results in the creation of a novel protein-coding capacity. Within certain genes, gene rearrangement is a normal part of development, facilitating the affinity maturation of B and T lymphocytes as well as class ...
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Definitions, 2020 A molecular abnormality indicating rearrangement of the KMT2A gene.
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Frontiers in Immunology, 2021 Multiple gene-driven programmed cell death 1 ligand 1 (PD-L1)-expressing non-small-cell lung cancer (NSCLC) is very rare. Previous studies have shown that patients with NSCLC with anaplastic lymphoma kinase (ALK) gene rearrangement rarely benefit from PD-
Wen Dong +4 more
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Definitions, 2020 A molecular abnormality indicating rearrangement gene.
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Lack of ROS1 Gene Rearrangement in Glioblastoma Multiforme. [PDF]
PLoS ONE, 2015 Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor, and the prognosis remains poor. Rearrangement of ROS1 gene, which was shown to have an oncogenic potential, was previously discovered in GBM cell lines.
Sun Min Lim +8 more
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Insights into the Evolution of Aphid Mitogenome Features from New Data and Comparative Analysis
Animals, 2022 The complete mitochondrial genomes and their rearrangement patterns can provide useful information for inferring evolutionary history of organisms. Aphids are one of the insect groups with some unique mitogenome features.
Hui Zhang +5 more
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