Cell, 2014 Reference EPFL-ARTICLE-198028doi:10.1016/j.cell.2014.01.060View record in Web of Science Record created on 2014-04-02, modified on 2017-05 ...
Andrey, Guillaume, Duboule, Denis
openaire +3 more sources
SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells
Nature Communications, 2018 The mechanism of resistance to EZH2 inhibitors in cancers with inactivating SWI/SNF mutations is unknown. Here, the authors demonstrate that the switch of the SWI/SNF catalytic subunits from SMARCA4 to SMARCA2 drives resistance to EZH2 inhibitors in ...
Shuai Wu +11 more
doaj +1 more source
Functional Characteristics of Gene Expression Motifs with Single and Dual Strategies of Regulation
, 2016 Transcriptional regulation by transcription factors and post-transcriptional regulation by microRNAs constitute two major modes of regulation of gene expression.
Bose, Indrani +2 more
core +1 more source
Origins of Binary Gene Expression in Post-transcriptional Regulation by MicroRNAs
, 2012 MicroRNA-mediated regulation of gene expression is characterised by some distinctive features that set it apart from unregulated and transcription factor-regulated gene expression. Recently, a mathematical model has been proposed to describe the dynamics
Bose, Indrani, Ghosh, Sayantari
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The regulation of Hox gene expression during animal development [PDF]
, 2013 Hox genes encode a family of transcriptional regulators that elicit distinct developmental programmes along the head-to-tail axis of animals. The specific regional functions of individual Hox genes largely reflect their restricted expression patterns ...
Alonso, Claudio R, Mallo, Moisés
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TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection
JHEP Reports, 2020 Background & Aims: HDV infection induces the most severe form of human viral hepatitis. However, the specific reasons for the severity of the disease remain unknown.
Carla Usai +9 more
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Regulation of translation in haloarchaea: 5'- and 3'-UTRs are essential and have to functionally interact in vivo [PDF]
, 2009 Recently a first genome-wide analysis of translational regulation using prokaryotic species had been performed which revealed that regulation of translational efficiency plays an important role in haloarchaea.
Mariam Brenneis +43 more
core +1 more source
TENT2, TUT4, and TUT7 selectively regulate miRNA sequence and abundance
Nature Communications, 2022 The authors reveal insights into miRNA tailing specificity of TENTs and their effect on miRNA levels by combinatory KOs of TENT2, TUT4 and TUT7. They show uridylation is linked to TENT2 and identify non-redundant functions between TUT4 and TUT7.
Acong Yang +5 more
doaj +1 more source
From obesity resistance to obesity prediction and prevention? [PDF]
, 2016 Comment on: Regulation of hypothalamic neuropeptides gene expression in diet induced obesity resistant rats: possible targets for obesity prediction?
Cassano, Tommaso, Gaetani, Silvana
core +4 more sources
Structural basis underlying viral hijacking of a histone chaperone complex
Nature Communications, 2016 The Epstein-Barr virus tegument protein BNRF1 is required for the establishment of selective viral gene expression during latency and interacts with the histone chaperone DAXX.
Hongda Huang +6 more
doaj +1 more source