Results 41 to 50 of about 3,161,105 (354)
From obesity resistance to obesity prediction and prevention? [PDF]
, 2016 Comment on: Regulation of hypothalamic neuropeptides gene expression in diet induced obesity resistant rats: possible targets for obesity prediction?
Cassano, Tommaso, Gaetani, Silvana
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed +5 more
wiley +1 more source
The Penn State Protein Ladder system for inexpensive protein molecular weight markers
Scientific Reports, 2021 We have created the Penn State Protein Ladder system to produce protein molecular weight markers easily and inexpensively (less than a penny a lane). The system includes plasmids which express 10, 15, 20, 30, 40, 50, 60, 80 and 100 kD proteins in E. coli.
Ryan T. Santilli +5 more
doaj +1 more source
Distance matters: the impact of gene proximity in bacterial gene regulation
, 2013 Following recent discoveries of colocalization of downstream-regulating genes in living cells, the impact of the spatial distance between such genes on the kinetics of gene product formation is increasingly recognized.
Metzler, Ralf, Pulkkinen, Otto
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Frequency-modulated nuclear localization bursts coordinate gene regulation [PDF]
, 2008 In yeast, the transcription factor Crz1 is dephosphorylated and translocates into the nucleus in response to extracellular calcium. Here we show, using time-lapse microscopy, that Crz1 exhibits short bursts of nuclear localization (typically lasting 2 ...
Cai, Long +2 more
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Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2
Nature Communications, 2020 3′ end of microRNAs binds to the PAZ domain of Argonaute (AGO) proteins. Here the authors show that terminal nucleotidyltransferases TUT4/7 and exonuclease DIS3L2 induce tailing and decay of 3’ end exposed-microRNAs in AGO PAZ mutant expressing- or ...
Acong Yang +6 more
doaj +1 more source
A linear mixed model approach to gene expression-tumor aneuploidy association studies. [PDF]
, 2019 Aneuploidy, defined as abnormal chromosome number or somatic DNA copy number, is a characteristic of many aggressive tumors and is thought to drive tumorigenesis.
Balanis, Nikolas G +3 more
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Optimal first-passage time in gene regulatory networks
, 2014 The inherent probabilistic nature of the biochemical reactions, and low copy number of species can lead to stochasticity in gene expression across identical cells.
Ghusinga, Khem Raj, Singh, Abhyudai
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Quantifying Dynamic Regulation in Metabolic Pathways with Nonparametric Flux Inference [PDF]
, 2019 One of the central tasks in systems biology is to understand how cells regulate their metabolism. Hierarchical regulation analysis is a powerful tool to study this regulation at the metabolic, gene-expression, and signaling levels.
He, Fei, Stumpf, Michael P H
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