Results 11 to 20 of about 786,474 (343)
The inferred cardiogenic gene regulatory network in the mammalian heart. [PDF]
PLoS ONE, 2014 Cardiac development is a complex, multiscale process encompassing cell fate adoption, differentiation and morphogenesis. To elucidate pathways underlying this process, a recently developed algorithm to reverse engineer gene regulatory networks was ...
Jason N Bazil +6 more
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Gene regulatory networks [PDF]
Proceedings of the National Academy of Sciences, 2005 The Special Feature on gene regulatory networks in this issue of PNAS highlights an emerging field in the biosciences: gene regulatory networks that control animal development. The complex control systems underlying development have probably been evolving for more than a billion years.
Eric, Davidson, Michael, Levin
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Gene-centered regulatory networks [PDF]
Briefings in Functional Genomics, 2009 Differential gene expression plays a critical role in the development and physiology of multicellular organisms. At a 'systems level' (e.g. at the level of a tissue, organ or whole organism), this process can be studied using gene regulatory network (GRN) models that capture physical and regulatory interactions between genes and their regulators.
Arda, H. Efsun, Walhout, Albertha J M
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Logic of gene regulatory networks [PDF]
Current Opinion in Biotechnology, 2007 Regulatory networks of transcription factors and signaling molecules lie at the heart of development. Their architecture implements logic functions whose execution propels cells from one regulatory state to the next, thus driving development forward.
Materna, Stefan C., Davidson, Eric H.
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Reconstruction of gene regulatory modules in cancer cell cycle by multi-source data integration. [PDF]
PLoS ONE, 2010 Precise regulation of the cell cycle is crucial to the growth and development of all organisms. Understanding the regulatory mechanism of the cell cycle is crucial to unraveling many complicated diseases, most notably cancer.
Yuji Zhang +4 more
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Synchrony in Gene Regulatory Networks
Physica D: Nonlinear phenomena, 2021 We consider two mathematical dynamical models of gene regulatory networks (GRNs) and obtain results on robust synchronization on these dynamical models based on the existing theoretical results in the coupled cell network formalism. We also explore the concepts of quotient networks and network lifting in the context of GRNs which are related to the ...
Aguiar, Manuela A. D. +2 more
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Supervised Learning of Gene Regulatory Networks [PDF]
Current Protocols in Plant Biology, 2020 AbstractIdentifying the entirety of gene regulatory interactions in a biological system offers the possibility to determine the key molecular factors that affect important traits on the level of cells, tissues, and whole organisms. Despite the development of experimental approaches and technologies for identification of direct binding of transcription ...
Razaghi-Moghadam, Zahra +1 more
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A gene regulatory network inference model based on pseudo-siamese network
BMC Bioinformatics, 2023 Motivation Gene regulatory networks (GRNs) arise from the intricate interactions between transcription factors (TFs) and their target genes during the growth and development of organisms.
Qian Wang +3 more
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Emergent adaptive behaviour of GRN-controlled simulated robots in a changing environment [PDF]
, 2016 We developed a bio-inspired robot controller combining an artificial genome with an agent-based control system. The genome encodes a gene regulatory network (GRN) that is switched on by environmental cues and, following the rules of transcriptional ...
Marchal, Kathleen +3 more
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A boolean model of the cardiac gene regulatory network determining first and second heart field identity. [PDF]
PLoS ONE, 2012 Two types of distinct cardiac progenitor cell populations can be identified during early heart development: the first heart field (FHF) and second heart field (SHF) lineage that later form the mature heart.
Franziska Herrmann +4 more
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