Results 31 to 40 of about 8,163,121 (296)

Approximate kernel reconstruction for time-varying networks

BioData Mining, 2019
Background Most existing algorithms for modeling and analyzing molecular networks assume a static or time-invariant network topology. Such view, however, does not render the temporal evolution of the underlying biological process as molecular networks ...
Gregory Ditzler, Nidhal Bouaynaya, Roman Shterenberg, Hassan M. Fathallah-Shaykh   +3 more
doaj   +1 more source

Reduction of the chemical master equation for gene regulatory networks using proper generalized decompositions [PDF]

, 2012
The numerical solution of the chemical master equation (CME) governing gene regulatory networks and cell signaling processes remains a challenging task owing to its complexity, exponentially growing with the number of species involved.
CHINESTA SORIA, Francisco, Chinesta, Francisco, CUETO, Elias, AMMAR, Amine   +3 more
core   +1 more source

Filtering for nonlinear genetic regulatory networks with stochastic disturbances [PDF]

, 2008
In this paper, the filtering problem is investigated for nonlinear genetic regulatory networks with stochastic disturbances and time delays, where the nonlinear function describing the feedback regulation is assumed to satisfy the sector condition, the ...
Liu, X, Wang, Z, Fraser, K, Lam, J, Wei, G   +4 more
core   +7 more sources

A method to construct gene regulatory networks to estimate and calculate time delays [PDF]

, 2013
In general, the motive of this research is to infer gene regulatory network in order to clarify the basis consequences of biological process at the molecular level.
Mohamad, Mohd. Saberi, Chai, Suk Phin
core   +1 more source

Correlated fluctuations carry signatures of gene regulatory network dynamics [PDF]

, 2010
The dynamics of transcriptional control involve small numbers of molecules and result in significant fluctuations in protein and mRNA concentrations.
Pakka, V. H., Pakka, Vijayanarasimha H., Prugel-Bennett, Adam, Prugel-Bennett, A., Adam Prügel-Bennett, Dasmahapatra, S., Pakka, Vijayanarasimha, Dasmahapatra, Srinandan, Vijayanarasimha H. Pakka, Srinandan Dasmahapatra   +9 more
core   +1 more source

Model Checking Gene Regulatory Networks [PDF]

, 2015
19 pages, 20 references, 4 ...
Mirco Giacobbe, Calin C. Guet, Ashutosh Gupta 0001, Thomas A. Henzinger, Tiago Paixão, Tatjana Petrov   +5 more
openaire   +5 more sources

Understanding Tissue-Specific Gene Regulation

Cell Reports, 2017
Summary: Although all human tissues carry out common processes, tissues are distinguished by gene expression patterns, implying that distinct regulatory programs control tissue specificity.
Abhijeet Rajendra Sonawane, John Platig, Maud Fagny, Cho-Yi Chen, Joseph Nathaniel Paulson, Camila Miranda Lopes-Ramos, Dawn Lisa DeMeo, John Quackenbush, Kimberly Glass, Marieke Lydia Kuijjer   +9 more
doaj   +1 more source

Variable levels of drift in tunicate cardiopharyngeal gene regulatory elements

EvoDevo, 2019
Background Mutations in gene regulatory networks often lead to genetic divergence without impacting gene expression or developmental patterning. The rules governing this process of developmental systems drift, including the variable impact of selective ...
William Colgan, Alexis Leanza, Ariel Hwang, Melissa B. DeBiasse, Isabel Llosa, Daniel Rodrigues, Hriju Adhikari, Guillermo Barreto Corona, Saskia Bock, Amanda Carillo-Perez, Meagan Currie, Simone Darkoa-Larbi, Daniel Dellal, Hanna Gutow, Pascha Hokama, Emily Kibby, Noah Linhart, Sophia Moody, Allison Naganuma, Diep Nguyen, Ryan Stanton, Sierra Stark, Cameron Tumey, Anthony Velleca, Joseph F. Ryan, Brad Davidson   +25 more
doaj   +1 more source

An extended Kalman filtering approach to modeling nonlinear dynamic gene regulatory networks via short gene expression time series [PDF]

, 2009
Copyright [2009] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Liu, Y, Liu, X, Wang, Z, Liang, Y, Vinciotti, V   +4 more
core   +1 more source

Gene Regulatory Networks in the Genomics Era

Genomics, Proteomics & Bioinformatics, 2013
The precise regulation of gene expression is critical to the normal development and biological function of all organisms. Dysregulation of gene expression during early development can result in a spectrum of failures ranging from minor defects to the termination of development.
Matthew Loose, Roger Patient, Xiangdong Fang, Hongxing Lei   +3 more
openaire   +5 more sources