Results 31 to 40 of about 8,545,689 (298)

Comprehensive information-based differential gene regulatory networks analysis (CIdrgn): Application to gastric cancer and chemotherapy-responsive gene network identification.

PLoS ONE, 2023
Biological condition-responsive gene network analysis has attracted considerable research attention because of its ability to identify pathways or gene modules involved in the underlying mechanisms of diseases.
Heewon Park, Seiya Imoto, Satoru Miyano
doaj   +2 more sources

Approximate kernel reconstruction for time-varying networks

BioData Mining, 2019
Background Most existing algorithms for modeling and analyzing molecular networks assume a static or time-invariant network topology. Such view, however, does not render the temporal evolution of the underlying biological process as molecular networks ...
Gregory Ditzler, Nidhal Bouaynaya, Roman Shterenberg, Hassan M. Fathallah-Shaykh   +3 more
doaj   +1 more source

GeRNet: a gene regulatory network tool [PDF]

Biosystems, 2017
Gene regulatory networks (GRNs) are crucial in every process of life since they govern the majority of the molecular processes. Therefore, the task of assembling these networks is highly important. In particular, the so called model-free approaches have an advantage modeling the complexities of dynamic molecular networks, since most of the gene ...
Julieta Sol Dussaut, Cristian Andrés Gallo, Fiorella Cravero, María Jimena Martínez, Jessica Andrea Carballido, Ignacio Ponzoni   +5 more
openaire   +4 more sources

Dynamic Bayesian networks in molecular plant science: inferring gene regulatory networks from multiple gene expression time series [PDF]

, 2011
To understand the processes of growth and biomass production in plants, we ultimately need to elucidate the structure of the underlying regulatory networks at the molecular level.
Dondelinger, F., Husmeier, D., Dondelinger, Frank, Dirk Husmeier, Frank Dondelinger, Husmeier, Dirk, Lebre, S., Sophie Lèbre, Lèbre, Sophie   +8 more
core   +1 more source

An extended Kalman filtering approach to modeling nonlinear dynamic gene regulatory networks via short gene expression time series [PDF]

, 2009
Copyright [2009] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Liu, Y, Liu, X, Wang, Z, Liang, Y, Vinciotti, V   +4 more
core   +1 more source

Model Checking Gene Regulatory Networks [PDF]

, 2015
19 pages, 20 references, 4 ...
Mirco Giacobbe, Calin C. Guet, Ashutosh Gupta 0001, Thomas A. Henzinger, Tiago Paixão, Tatjana Petrov   +5 more
openaire   +5 more sources

Correlated fluctuations carry signatures of gene regulatory network dynamics [PDF]

, 2010
The dynamics of transcriptional control involve small numbers of molecules and result in significant fluctuations in protein and mRNA concentrations.
Pakka, V. H., Pakka, Vijayanarasimha H., Prugel-Bennett, Adam, Prugel-Bennett, A., Adam Prügel-Bennett, Dasmahapatra, S., Pakka, Vijayanarasimha, Dasmahapatra, Srinandan, Vijayanarasimha H. Pakka, Srinandan Dasmahapatra   +9 more
core   +1 more source

Understanding Tissue-Specific Gene Regulation

Cell Reports, 2017
Summary: Although all human tissues carry out common processes, tissues are distinguished by gene expression patterns, implying that distinct regulatory programs control tissue specificity.
Abhijeet Rajendra Sonawane, John Platig, Maud Fagny, Cho-Yi Chen, Joseph Nathaniel Paulson, Camila Miranda Lopes-Ramos, Dawn Lisa DeMeo, John Quackenbush, Kimberly Glass, Marieke Lydia Kuijjer   +9 more
doaj   +1 more source

Variable levels of drift in tunicate cardiopharyngeal gene regulatory elements

EvoDevo, 2019
Background Mutations in gene regulatory networks often lead to genetic divergence without impacting gene expression or developmental patterning. The rules governing this process of developmental systems drift, including the variable impact of selective ...
William Colgan, Alexis Leanza, Ariel Hwang, Melissa B. DeBiasse, Isabel Llosa, Daniel Rodrigues, Hriju Adhikari, Guillermo Barreto Corona, Saskia Bock, Amanda Carillo-Perez, Meagan Currie, Simone Darkoa-Larbi, Daniel Dellal, Hanna Gutow, Pascha Hokama, Emily Kibby, Noah Linhart, Sophia Moody, Allison Naganuma, Diep Nguyen, Ryan Stanton, Sierra Stark, Cameron Tumey, Anthony Velleca, Joseph F. Ryan, Brad Davidson   +25 more
doaj   +1 more source

Gene Regulatory Networks in the Genomics Era

Genomics, Proteomics & Bioinformatics, 2013
The precise regulation of gene expression is critical to the normal development and biological function of all organisms. Dysregulation of gene expression during early development can result in a spectrum of failures ranging from minor defects to the termination of development.
Matthew Loose, Roger Patient, Xiangdong Fang, Hongxing Lei   +3 more
openaire   +5 more sources