Results 31 to 40 of about 474,387 (314)

Fan-out in gene regulatory networks [PDF]

open access: yesJournal of Biological Engineering, 2010
In synthetic biology, gene regulatory circuits are often constructed by combining smaller circuit components. Connections between components are achieved by transcription factors acting on promoters. If the individual components behave as true modules and certain module interface conditions are satisfied, the function of the composite circuits can in ...
Sauro Herbert M, Kim Kyung H
openaire   +4 more sources

Dynamic Bayesian networks in molecular plant science: inferring gene regulatory networks from multiple gene expression time series [PDF]

open access: yes, 2011
To understand the processes of growth and biomass production in plants, we ultimately need to elucidate the structure of the underlying regulatory networks at the molecular level.
Dondelinger, F.   +8 more
core   +1 more source

Current approaches to gene regulatory network modelling

open access: yesBMC Bioinformatics, 2007
Many different approaches have been developed to model and simulate gene regulatory networks. We proposed the following categories for gene regulatory network models: network parts lists, network topology models, network control logic models, and dynamic
Brazma Alvis, Schlitt Thomas
doaj   +1 more source

Dynamical Criticality in Gene Regulatory Networks [PDF]

open access: yesComplexity, 2018
A well‐known hypothesis, with far‐reaching implications, is that biological evolution should preferentially lead to states that are dynamically critical. In previous papers, we showed that a well‐known model of genetic regulatory networks, namely, that of random Boolean networks, allows one to study in depth the relationship between the dynamical ...
Villani, Marco   +3 more
openaire   +3 more sources

Modelling nonstationary gene regulatory processes [PDF]

open access: yes, 2010
An important objective in systems biology is to infer gene regulatory networks from postgenomic data, and dynamic Bayesian networks have been widely applied as a popular tool to this end.
Husmeier, D.   +5 more
core   +1 more source

GeRNet: a gene regulatory network tool [PDF]

open access: yesBiosystems, 2017
Gene regulatory networks (GRNs) are crucial in every process of life since they govern the majority of the molecular processes. Therefore, the task of assembling these networks is highly important. In particular, the so called model-free approaches have an advantage modeling the complexities of dynamic molecular networks, since most of the gene ...
Julieta Sol Dussaut   +5 more
openaire   +3 more sources

Approximate kernel reconstruction for time-varying networks

open access: yesBioData Mining, 2019
Background Most existing algorithms for modeling and analyzing molecular networks assume a static or time-invariant network topology. Such view, however, does not render the temporal evolution of the underlying biological process as molecular networks ...
Gregory Ditzler   +3 more
doaj   +1 more source

Statistical inference of regulatory networks for circadian regulation [PDF]

open access: yes, 2014
The work described in the present article is part of the TiMet project on linking the circadian clock to metabolism in plants. TiMet is a collaborative project (Grant Agreement 245143) funded by the European Commission FP7, in response to call FP7-KBBE ...
Aderhold, Andrej   +2 more
core   +1 more source

Understanding Tissue-Specific Gene Regulation

open access: yesCell Reports, 2017
Summary: Although all human tissues carry out common processes, tissues are distinguished by gene expression patterns, implying that distinct regulatory programs control tissue specificity.
Abhijeet Rajendra Sonawane   +9 more
doaj   +1 more source

Model Checking Gene Regulatory Networks [PDF]

open access: yes, 2015
19 pages, 20 references, 4 ...
Mirco Giacobbe   +5 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy