Results 11 to 20 of about 8,545,689 (298)
Synchrony in Gene Regulatory Networks
Physica D: Nonlinear phenomena, 2021 We consider two mathematical dynamical models of gene regulatory networks (GRNs) and obtain results on robust synchronization on these dynamical models based on the existing theoretical results in the coupled cell network formalism. We also explore the concepts of quotient networks and network lifting in the context of GRNs which are related to the ...
Aguiar, Manuela A. D. +2 more
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Quantum gene regulatory networks
npj Quantum Information, 2022 AbstractIn this work, we present a quantum circuit model for inferring gene regulatory networks (GRNs) from single-cell transcriptomic data. The model employs qubit entanglement to simulate interactions between genes, resulting in competitive performance and promising potential for further exploration.
Cristhian Roman-Vicharra, James J. Cai
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Gene-centered regulatory networks [PDF]
Briefings in Functional Genomics, 2009 Differential gene expression plays a critical role in the development and physiology of multicellular organisms. At a 'systems level' (e.g. at the level of a tissue, organ or whole organism), this process can be studied using gene regulatory network (GRN) models that capture physical and regulatory interactions between genes and their regulators.
Arda, H. Efsun, Walhout, Albertha J M
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Cancer Informatics, 2006 Background Cell cycle is an important clue to unravel the mechanism of cancer cells. Recently, expression profiles of cDNA microarray data of Cancer cell cycle are available for the information of dynamic interactions among Cancer cell cycle related ...
Cheng-Wei Li +2 more
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Inferring gene dependency network specific to phenotypic alteration based on gene expression data and clinical information of breast cancer. [PDF]
PLoS ONE, 2014 Although many methods have been proposed to reconstruct gene regulatory network, most of them, when applied in the sample-based data, can not reveal the gene regulatory relations underlying the phenotypic change (e.g. normal versus cancer). In this paper,
Xionghui Zhou, Juan Liu
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Supervised Learning of Gene Regulatory Networks [PDF]
Current Protocols in Plant Biology, 2020 AbstractIdentifying the entirety of gene regulatory interactions in a biological system offers the possibility to determine the key molecular factors that affect important traits on the level of cells, tissues, and whole organisms. Despite the development of experimental approaches and technologies for identification of direct binding of transcription ...
Razaghi-Moghadam, Zahra +1 more
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A gene regulatory network inference model based on pseudo-siamese network
BMC Bioinformatics, 2023 Motivation Gene regulatory networks (GRNs) arise from the intricate interactions between transcription factors (TFs) and their target genes during the growth and development of organisms.
Qian Wang +3 more
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Gene regulatory networks for development [PDF]
Proceedings of the National Academy of Sciences, 2005 The genomic program for development operates primarily by the regulated expression of genes encoding transcription factors and components of cell signaling pathways. This program is executed by cis-regulatory DNAs (e.g., enhancers and silencers) that control gene expression.
Levine, Michael, Davidson, Eric H.
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BMC Bioinformatics, 2011 Background Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes.
Dickerson Julie A +2 more
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Frontiers in Bioinformatics, 2022 Brain tumor research has been stapled for human health while brain network research is crucial for us to understand brain activity. Here the structural controllability theory is applied to study three human brain-specific gene regulatory networks ...
Zhihua Chen, Siyuan Chen, Xiaoli Qiang
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