Results 21 to 30 of about 786,474 (343)
Building developmental gene regulatory networks [PDF]
Birth Defects Research Part C: Embryo Today: Reviews, 2009 AbstractAnimal development is an elaborate process programmed by genomic regulatory instructions. Regulatory genes encode transcription factors and signal molecules, and their expression is under the control of cisâregulatory modules that define the logic of transcriptional responses to the inputs of other regulatory genes.
Li, Enhu, Davidson, Eric H.
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Stochastic neural network models for gene regulatory networks [PDF]
, 2003 Recent advances in gene-expression profiling technologies provide large amounts of gene expression data. This raises the possibility for a functional understanding of genome dynamics by means of mathematical modelling.
Burrage, K., Tian, T.
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Wheat leaf senescence and its regulatory gene network
Crop Journal, 2021 Wheat leaf senescence is a developmental process that involves expressional changes in thousands of genes that ultimately impact grain protein content (GPC), grain yield (GY), and nitrogen use efficiency.
Nigarin Sultana +3 more
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Time-delayed models of gene regulatory networks [PDF]
, 2015 We discuss different mathematical models of gene regulatory networks as relevant to the onset and development of cancer. After discussion of alternativemodelling approaches, we use a paradigmatic two-gene network to focus on the role played by time ...
Blyuss, K B +3 more
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Current approaches to gene regulatory network modelling
BMC Bioinformatics, 2007 Many different approaches have been developed to model and simulate gene regulatory networks. We proposed the following categories for gene regulatory network models: network parts lists, network topology models, network control logic models, and dynamic
Brazma Alvis, Schlitt Thomas
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Evolutionary plasticity of developmental gene regulatory network architecture [PDF]
, 2007 Sea stars and sea urchins evolved from a last common ancestor that lived at the end of the Cambrian, approximately half a billion years ago. In a previous comparative study of the gene regulatory networks (GRNs) that embody the genomic program for ...
Britten +25 more
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Single-cell transcriptomics unveils gene regulatory network plasticity
Genome Biology, 2019 Background Single-cell RNA sequencing (scRNA-seq) plays a pivotal role in our understanding of cellular heterogeneity. Current analytical workflows are driven by categorizing principles that consider cells as individual entities and classify them into ...
Giovanni Iacono +2 more
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Gene regulatory network reconfiguration in direct lineage reprogramming
Stem Cell Reports, 2023 Summary: In direct lineage conversion, transcription factor (TF) overexpression reconfigures gene regulatory networks (GRNs) to reprogram cell identity.
Kenji Kamimoto +6 more
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Introduction to gene regulatory networks [PDF]
Proceedings of the Genetic and Evolutionary Computation Conference Companion, 2015 Gene regulatory networks are a central mechanism in the regulation of gene expression in all living organisms? cells. Their functioning is nowadays very well understood: they are based on the production of proteins enhanced or inhibited by other proteins inside and outside the cells. This produces a complex dynamics with which, with the exact same DNA,
Sylvain Cussat-Blanc, Wolfgang Banzhaf
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Stochastic models and numerical algorithms for a class of regulatory gene networks [PDF]
, 2008 Regulatory gene networks contain generic modules like those involving feedback loops, which are essential for the regulation of many biological functions.
Fournier, Thomas +5 more
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