Results 41 to 50 of about 261,824 (309)
Integrated module and gene-specific regulatory inference implicates upstream signaling networks. [PDF]
PLoS Computational Biology, 2013 Regulatory networks that control gene expression are important in diverse biological contexts including stress response and development. Each gene's regulatory program is determined by module-level regulation (e.g.
Sushmita Roy +5 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
BMC Bioinformatics, 2019 Background Mathematical models of biological networks can provide important predictions and insights into complex disease. Constraint-based models of cellular metabolism and probabilistic models of gene regulatory networks are two distinct areas that ...
Han Yu, Rachael Hageman Blair
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Emergence of co-expression in gene regulatory networks.
PLoS ONE, 2021 Transcriptomes are known to organize themselves into gene co-expression clusters or modules where groups of genes display distinct patterns of coordinated or synchronous expression across independent biological samples.
Wencheng Yin +4 more
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Algorithms, 2021 The reconstruction of gene regulatory networks based on gene expression data can effectively uncover regulatory relationships between genes and provide a deeper understanding of biological control processes.
Kuan Liu +3 more
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Adaptive gene regulatory networks [PDF]
EPL (Europhysics Letters), 2009 5 pages ...
Stauffer, Franck, Berg, Johannes
openaire +2 more sources
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
CoryneRegNet 4.0 – A reference database for corynebacterial gene regulatory networks
BMC Bioinformatics, 2007 Background Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of microorganisms deduced from literature-derived knowledge, computer predictions ...
Baumbach Jan
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A publish-subscribe model of genetic networks. [PDF]
PLoS ONE, 2008 We present a simple model of genetic regulatory networks in which regulatory connections among genes are mediated by a limited number of signaling molecules.
Brett Calcott +2 more
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A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source