Results 161 to 170 of about 1,756,365 (358)

Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.

, 1996
Jean Christophe Bories, Jocelyne Demengeot, Laurie A. Davidson, F W Alt   +3 more
openalex   +2 more sources

Differential regulation of target genes by different alleles of the segmentation gene hunchback in Drosophila. [PDF]

, 1994
Martin Hülskamp, Wolfgang Lukowitz, Anke Beermann, Gerald Glaser, Diethard Tautz   +4 more
openalex   +1 more source

Spatiotemporal gene targeting in the mouse corneal endothelium. [PDF]

Taiwan J Ophthalmol, 2023
Lee J, Heur M.
europepmc   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Study of the homologous recombination genetic system to improve genetic transformation of wheat

Czech Journal of Genetics and Plant Breeding, 2005
A. De Bustos, R. Pérez, N. Jouve
doaj   +1 more source

Nanotechnology prospects in brain therapeutics concerning gene-targeting and nose-to-brain administration. [PDF]

iScience, 2023
Wu DD, Salah YA, Ngowi EE, Zhang YX, Khattak S, Khan NH, Wang Y, Li T, Guo ZH, Wang YM, Ji XY.   +10 more
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Eat4Genes: a bioinformatic rational gene targeting app and prototype model for improving human health. [PDF]

Front Nutr, 2023
Ford ML, Cooley JM, Sripada V, Xu Z, Erickson JS, Bennett KP, Crawford DR.   +6 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Knocking out the pptA gene in Aspergillus fumigatus could result in new protein profile and promising targets for antifungals

, 2018

openalex   +1 more source