Results 251 to 260 of about 12,185,719 (426)

A method for overproduction of a protein of a target gene in Escherichia coli.

, 1988
Tatsurou Shibui, Michiru Uchida-Kamizono, Yutaka Teranishi   +2 more
openalex   +2 more sources

Reexamination of Gene Targeting Frequency as a Function of the Extent of Homology between the Targeting Vector and the Target Locus [PDF]

, 1992
Chu‐Xia Deng, Mario R. Capecchi
openalex   +1 more source

Study of the homologous recombination genetic system to improve genetic transformation of wheat

Czech Journal of Genetics and Plant Breeding, 2005
A. De Bustos, R. Pérez, N. Jouve
doaj   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Human RNase P: overview of a ribonuclease of interrelated molecular networks and gene-targeting systems. [PDF]

RNA, 2023
Jarrous N, Liu F.
europepmc   +1 more source

GSH1, which encodes gamma-glutamylcysteine synthetase, is a target gene for yAP-1 transcriptional regulation. [PDF]

, 1994
A L Wu, W. Scott Moye‐Rowley
openalex   +1 more source

Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos

Cell, 2014
Yuyu Niu, Bin Shen, Yiqiang Cui, Yongchang Chen, Jianying Wang, Lei Wang, Yu Kang, Xiao-Yang Zhao, W. Si, Wei Li, A. Xiang, Jiankui Zhou, Xuejiang Guo, Ye Bi, Chenyang Si, Bian Hu, Guoying Dong, Hong Wang, Zuo-min Zhou, Tianqing Li, apple apple, X. Pu, F. Wang, Shaohui Ji, Qi Zhou, Xingxu Huang, W. Ji, J. Sha   +27 more
semanticscholar   +1 more source

Hijacking the BAF complex: the mechanistic interplay of ARID1A and EWS::FLI1 in Ewing sarcoma

Molecular Oncology, Volume 19, Issue 4, Page 961-964, April 2025.
Ewing sarcoma is driven by the EWS::FLI1 fusion protein, which disrupts gene expression by hijacking the BAF complex via ARID1A. ARID1A's ability to form biomolecular condensates is crucial for tumor growth, making it a potential therapeutic target. However, targeting these transient condensates is challenging, requiring further research. Ewing sarcoma,
Erich J. Sohn, David S. Libich
wiley   +1 more source

Gene targeting techniques for Huntington's disease. [PDF]

Ageing Res Rev, 2021
Fields E, Vaughan E, Tripu D, Lim I, Shrout K, Conway J, Salib N, Lee Y, Dhamsania A, Jacobsen M, Woo A, Xue H, Cao K.   +12 more
europepmc   +1 more source

Targeted disruption of the Hexa gene results in mice with biochemical and pathologic features of Tay-Sachs disease. [PDF]

, 1994
Shoji Yamanaka, Mark D. Johnson, Alexander Grinberg, H Westphal, Jacqueline N. Crawley, Masako Taniike, Kotaro Suzuki, Richard L. Proia   +7 more
openalex   +1 more source