Results 281 to 290 of about 12,185,719 (426)

Gut microbiota diversity is prognostic and associated with benefit from chemo‐immunotherapy in metastatic triple‐negative breast cancer

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1229-1243, April 2025.
We assessed the associations between the gut microbiota and outcome in metastatic triple‐negative breast cancer patients treated with chemotherapy alone or chemotherapy in combination with immunotherapy. Our data indicate that high gut microbiota alpha diversity was associated with improved clinical outcome and with benefit from immunotherapy.
Andreas Ullern   +8 more
wiley   +1 more source

A New EBS2b-IBS2b Base Paring (A-8/T-8) Improved the Gene-Targeting Efficiency of Thermotargetron in Escherichia coli. [PDF]

open access: yesMicrobiol Spectr, 2023
Cui G   +14 more
europepmc   +1 more source

An Enhanced Gene Targeting Toolkit for Drosophila: Golic+

open access: yesGenetics, 2015
Hui-Min Chen   +4 more
semanticscholar   +1 more source

Vertical inhibition of p110α/AKT and N‐cadherin enhances treatment efficacy in PIK3CA‐aberrated ovarian cancer cells

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1132-1154, April 2025.
PIK3CA amplification and PIK3CA mutation enhance ovarian tumorigenicity through an activation of AKT, which phosphorylates YAP at Ser127. This Ser127 phosphorylation leads to the retention of YAP in the cytoplasm and triggers RAC1 activity, promoting cell migration. Additionally, AKT activation increases expression of N‐cadherin, which further enhances
Shibo Zhang   +6 more
wiley   +1 more source

Enhancing CRISPR-Cas-based gene targeting in tomato using a dominant-negative ku80. [PDF]

open access: yesHortic Res
Vu TV   +7 more
europepmc   +1 more source

Cre recombinase microinjection for single-cell tracing and localised gene targeting.

open access: yesDevelopment, 2023
Sendra M   +6 more
europepmc   +1 more source

Gene Targeting to the Cerebral Cortex Following Intranasal Administration of Polyplexes. [PDF]

open access: yesPharmaceutics, 2022
Petkova AI   +4 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy