Results 21 to 30 of about 617,722 (336)
Research in Pharmaceutical Sciences, 2020 Background and purpose: The optimization of an effective non-viral gene delivery method for genetic manipulation of primary human T cells has been a major challenge in immunotherapy researches.
Ilnaz Rahimmanesh +2 more
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Calcium Based Non-viral Gene Delivery: An Overview of Methodology and Applications [PDF]
Acta Medica Iranica, 2010 Application of therapeutic gene transfer in the treatment of genetic diseases is a notable progress but there are some disadvantages and limitations in it. The process of overcoming these barriers is a drastic change in gene delivery.
Kianoush Khosravi-Darani +3 more
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Carbohydrate receptor-mediated gene transfer to human T leukaemic cells [PDF]
, 1994 The mucin-type carbohydrate Tn cryptantigen (GalNAcα1-O-Ser/Thr, where GalNAc is N-acetyl-D-galactosamine) is expressed in many carcinomas, in haemopoietic disorders including the Tn syndrome, and on human immunodeficiency virus (HIV) coat glycoproteins,
Berger, Eric G. +8 more
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The effects of different combinations and varying concentrations of growth regulators on the regeneration of selected Turkish cultivars of melon [PDF]
, 2013 Cucurbits are an economically important family of plants. The majority of the vegetable production in Turkey, for example, derives from the species beloning to the family Cucurbitaceae. Despite the importance of cucurbits among vegetable crops worldwide,
Cetiner, Selim +2 more
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Biomédica: revista del Instituto Nacional de Salud, 2008 Introducción. La mucopolisacaridosis IV A (Morquio A) es una enfermedad de depósito lisosómico causada por la deficiencia en la actividad de la enzima N-acetil-galactosamina- 6-sulfato-sulfatasa que produce la acumulación intralisosómica de queratán y ...
Luis Alejandro Barrera +6 more
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Magnetofection potentiates gene delivery to cultured endothelial cells [PDF]
, 2003 Modification of cellular functions by overexpression of genes is increasingly practised for research of signalling pathways, but restricted by limitations of low efficiency. We investigated whether the novel technique of magnetofection (MF) could enhance
Gloe, Torsten +4 more
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A transfer-learning approach to feature extraction from cancer transcriptomes with deep autoencoders [PDF]
, 2019 Publicado en Lecture Notes in Computer Science.The diagnosis and prognosis of cancer are among the more challenging tasks that oncology medicine deals with.
A Bashiri +13 more
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Pharmaceutical Biology, 2018 Context: Polypropylenimine (PPI), a cationic dendrimer with defined structure and positive surface charge, is a potent non-viral vector. Dexamethasone (Dexa) conveys to the nucleus through interaction with its intracellular receptor.
Bizhan Malaekeh-Nikouei +4 more
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Factors influencing the production of recombinant SV40 vectors [PDF]
, 2004 Most gene therapy approaches employ viral vectors for gene delivery. Ideally, these vectors should be produced at high titer and purity with well-established protocols.
Fortes, P. (Puri) +3 more
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Genetic Modification of T Cells
Biomedicines, 2016 Gene transfer technology and its application to human gene therapy greatly expanded in the last decade. One area of investigation that appears particularly promising is the transfer of new genetic material into T cells for the potential treatment of ...
Richard A. Morgan, Benjamin Boyerinas
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