Results 31 to 40 of about 625,112 (296)

Liposomes as a gene delivery system

open access: yesBrazilian Journal of Medical and Biological Research, 1999
Gene therapy is an active field that has progressed rapidly into clinical trials in a relatively short time. The key to success for any gene therapy strategy is to design a vector able to serve as a safe and efficient gene delivery vehicle.
C. Ropert
doaj   +1 more source

Functional knowledge transfer for high-accuracy prediction of under-studied biological processes. [PDF]

open access: yesPLoS Computational Biology, 2013
A key challenge in genetics is identifying the functional roles of genes in pathways. Numerous functional genomics techniques (e.g. machine learning) that predict protein function have been developed to address this question.
Christopher Y Park   +7 more
doaj   +1 more source

Asymmetric somatic plant hybridization : status and applications [PDF]

open access: yes, 2013
To create asymmetric somatic hybrids, the genome of the so-called donor protoplast is fragmented prior to protoplast fusion. As a result, only a limited amount of the donor genome is transferred to the fusion product.
Deryckere, Dieter   +4 more
core   +2 more sources

Impact of baculoviral transduction of fluorescent actin on cellular forces

open access: yesEuropean Journal of Cell Biology, 2023
Live staining of actin brings valuable information in the field of mechanobiology. Gene transfer of GFP-actin has been reported to disturb cell rheological properties while gene transfer of fluorescent actin binding proteins was not.
Sara Bouizakarne   +2 more
doaj   +1 more source

A flow cytometry technique for measuring chromosome-mediated gene transfer [PDF]

open access: yesCytometry, 2001
Using artificial chromosome expression systems (ACes), we have developed a unique and rapid screening technique to quantify delivery of foreign DNA into cells in vitro. Delivery was measured within 24 h after transfection, using flow cytometry to detect the transfer of ACes labeled with thymidine analogue.
S, Vanderbyl, N, MacDonald, G, de Jong
openaire   +2 more sources

Stable Feature Selection for Biomarker Discovery [PDF]

open access: yes, 2010
Feature selection techniques have been used as the workhorse in biomarker discovery applications for a long time. Surprisingly, the stability of feature selection with respect to sampling variations has long been under-considered.
He, Zengyou, Yu, Weichuan
core   +2 more sources

Gene Therapy in the Management of Erectile Dysfunction (ED): Past, Present, and Future

open access: yesThe Scientific World Journal, 2009
In the past, many researchers considered viral vectors to be the most promising candidates to transfer genetic material into the corpora for the treatment of erectile dysfunction. However, at present, no viral vectors have progressed to human trials.
Arnold Melman, Kelvin P. Davies
doaj   +1 more source

Small extracellular vesicle DNA-mediated horizontal gene transfer as a driving force for tumor evolution: Facts and riddles

open access: yesFrontiers in Oncology, 2022
The basis of the conventional gene-centric view on tumor evolution is that vertically inherited mutations largely define the properties of tumor cells.
Gábor Valcz   +14 more
doaj   +1 more source

An Overview of the Use of Neural Networks for Data Mining Tasks [PDF]

open access: yes, 2012
In the recent years the area of data mining has experienced a considerable demand for technologies that extract knowledge from large and complex data sources.
Alberts B   +22 more
core   +1 more source

TT2013 meeting report: the transgenic technology meeting visits Asia for the first time [PDF]

open access: yes, 2013
The 11th Transgenic Technology meeting was held in Guangzhou, China on 25th–27th February 2013. Over 300 scientists and students from round the world gathered to hear the latest developments in the technologies underpinning the creation of transgenic and
Strathdee, D., Whitelaw, C.B.A.
core   +3 more sources

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