Results 31 to 40 of about 582,689 (334)

The effects of different combinations and varying concentrations of growth regulators on the regeneration of selected Turkish cultivars of melon [PDF]

open access: yes, 2013
Cucurbits are an economically important family of plants. The majority of the vegetable production in Turkey, for example, derives from the species beloning to the family Cucurbitaceae. Despite the importance of cucurbits among vegetable crops worldwide,
Cetiner, Selim   +2 more
core   +2 more sources

Genetic Modification of T Cells

open access: yesBiomedicines, 2016
Gene transfer technology and its application to human gene therapy greatly expanded in the last decade. One area of investigation that appears particularly promising is the transfer of new genetic material into T cells for the potential treatment of ...
Richard A. Morgan, Benjamin Boyerinas
doaj   +1 more source

Gene therapy:the potential applicability of gene transfer technology to the human germline [PDF]

open access: yes, 2004
The theoretical possibility of applying gene transfer methodologies to the human germline is explored. Transgenic methods for genetically manipulating embryos may in principle be applied to humans.
Smith, Kevin R.
core   +2 more sources

Highly efficient retrograde gene transfer into motor neurons by a lentiviral vector pseudotyped with fusion glycoprotein. [PDF]

open access: yesPLoS ONE, 2013
The development of gene therapy techniques to introduce transgenes that promote neuronal survival and protection provides effective therapeutic approaches for neurological and neurodegenerative diseases.
Miyabi Hirano   +5 more
doaj   +1 more source

A Microfluidic System of Gene Transfer by Ultrasound

open access: yesMicromachines, 2022
Ultrasonic gene transfer has advantages beyond other cell transfer techniques because ultrasound does not directly act on cells, but rather pushes the gene fragments around the cells into cells through an acoustic hole effect. Most examples reported were
Cuimin Sun   +6 more
doaj   +1 more source

Development of alternative gene transfer techniques for ex vivo and in vivo gene therapy in a canine model

open access: yesRegenerative Therapy, 2021
Introduction: Gene therapy have recently attracted much attention as a curative therapeutic option for inherited single gene disorders such as hemophilia.
Masashi Noda   +11 more
doaj  

Factors influencing the production of recombinant SV40 vectors [PDF]

open access: yes, 2004
Most gene therapy approaches employ viral vectors for gene delivery. Ideally, these vectors should be produced at high titer and purity with well-established protocols.
Fortes, P. (Puri)   +3 more
core   +1 more source

Magnetofection potentiates gene delivery to cultured endothelial cells [PDF]

open access: yes, 2003
Modification of cellular functions by overexpression of genes is increasingly practised for research of signalling pathways, but restricted by limitations of low efficiency. We investigated whether the novel technique of magnetofection (MF) could enhance
Gloe, Torsten   +4 more
core   +1 more source

Liposomes as a gene delivery system

open access: yesBrazilian Journal of Medical and Biological Research, 1999
Gene therapy is an active field that has progressed rapidly into clinical trials in a relatively short time. The key to success for any gene therapy strategy is to design a vector able to serve as a safe and efficient gene delivery vehicle.
C. Ropert
doaj   +1 more source

Functional knowledge transfer for high-accuracy prediction of under-studied biological processes. [PDF]

open access: yesPLoS Computational Biology, 2013
A key challenge in genetics is identifying the functional roles of genes in pathways. Numerous functional genomics techniques (e.g. machine learning) that predict protein function have been developed to address this question.
Christopher Y Park   +7 more
doaj   +1 more source

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