Results 11 to 20 of about 1,017,855 (122)

A Case of Suspected Adverse Reactions to Sirolimus in the Treatment of Generalized Lymphatic Anomaly [PDF]

Case Reports in Pediatrics, 2019
Generalized lymphatic anomaly (GLA) is characterized by diffuse or multicentric proliferation of dilated lymphatic vessels resembling common lymphatic malformation, and thoracic lesions can be related to a poor prognosis.
Takayuki Fujii, Ryuichi Shimono, Aya Tanaka, Hiroto Katami   +3 more
doaj   +4 more sources

Neonatal Generalized Lymphatic Anomaly with Skin Involvement [PDF]

Annals of Dermatology, 2021
Generalized lymphatic anomaly (GLA) is a rare congenital disorder of lymphatic development, presenting with multiple lymphatic malformations in different organs and tissues. Here, we present a case of a female neonate prenatally diagnosed with foetal hydrops and a mediastinal cystic lymphatic malformation that showed postnatal expansive and ...
Gordana Markovic-Sovtic, Slavisa Djuricic, Aleksandar Sovtic, Predrag Minic, Zorica Rakonjac, Isabel Colmenero   +5 more
openaire   +5 more sources

Simple Lymphangioma to Generalized Lymphatic Anomaly: Role of Imaging in Disclosure of a Rare and Morbid Disease [PDF]

Case Reports in Radiology, 2015
Generalized lymphatic anomaly is a rare multisystem congenital disorder in which multiple organs are involved. Imaging features often overlap with other complex lymphatic anomalies and diagnosis is difficult.
Manoj Joshi, Dilip S. Phansalkar
doaj   +2 more sources

Generalized lymphatic anomaly in a pediatric patient manifesting as a rare presentation of hemorrhagic pleural effusion: a case report

BMC Pediatrics
Background Generalized lymphatic anomaly (GLA) is a rare congenital lymphatic malformation (LM) characterized by multiple infiltrating lymphangiomas in various tissues.
Xuehong Zhang, Jiuling Wang, Shouxing Duan, Yongping Yan, Libin Wang   +4 more
doaj   +2 more sources

Somatic activating mutations in PIK3CA cause generalized lymphatic anomaly [PDF]

Journal of Experimental Medicine, 2018
Generalized lymphatic anomaly (GLA) is a vascular disorder characterized by diffuse or multifocal lymphatic malformations (LMs). The etiology of GLA is poorly understood. We identified four distinct somatic PIK3CA variants (Glu542Lys, Gln546Lys, His1047Arg, and His1047Leu) in tissue samples from five out of nine patients with GLA.
Lara Rodriguez-Laguna, Noelia Agra, Kristina Ibañez, Gloria Oliva-Molina, Gema Gordo, Noor Khurana, Devon Hominick, María Beato, Isabel Colmenero, Gonzalo Herranz, Juan M. Torres Canizalez, Rebeca Rodríguez Pena, Elena Vallespín, Rubén Martín-Arenas, Ángela del Pozo, Cristina Villaverde, Ana Bustamante, Carmen Ayuso, Pablo Lapunzina, Juan C. Lopez-Gutierrez, Michael T. Dellinger, Victor Martinez-Glez   +21 more
openaire   +5 more sources

Deep Cervical Lymphovenous Anastomoses Improved Brain Function and Internal Neck Edema in Central Lymphatic Anomaly Associated with 13q Deletion Syndrome

Plastic and Reconstructive Surgery, Global Open
Summary:. We report a case of a 21-year-old woman with 13q deletion syndrome, a rare chromosomal disorder associated with developmental delays, craniofacial dysmorphism, and multiorgan abnormalities associated with central conducting lymphatic anomaly ...
Donata von Reibnitz, MD, Jacqueline Plau, PhD, Gilbert D. Puippe, MD, Claus C. Pieper, MD, Epameinondas Gousopoulos, MD, PhD, Nicole Lindenblatt, MD   +5 more
doaj   +2 more sources

Lymphatic malformations involving the thorax in children: a retrospective cohort study

BMC Pulmonary Medicine
Background Lymphatic malformations (LMs) involving the thorax are rare, with limited clinical understanding. We aimed to summarize the classification, clinical features, treatment, and prognosis of thoracic LMs, and to improve disease management and ...
Wenting Han, Haiming Yang, Jinrong Liu, Huimin Li, Hui Xu, Hui Liu, Xiaolei Tang, Shunying Zhao   +7 more
doaj   +2 more sources

Generalized lymphatic anomaly: A case report

, 2019
Complex Lymphatic Anomalies are a group of rare diseases characterized by a non-neoplastic proliferation of lymphatic vessels. They include Generalized Lymphatic Anomalies and Kaposiform Lymphangiomatosis (both with involvement of visceral organs and bone with multifocal and non-progressive osteolysis) and Gorham-Stout Disease (characterized by a ...
Figliomeni A., Franchi A., Zampa V., Capanna R., Mazzantini M   +4 more
openaire   +2 more sources

Imatinib Treatment of Lymphangiomatosis (Generalized Lymphatic Anomaly) [PDF]

Journal of the National Comprehensive Cancer Network, 2016
Lymphangiomatosis (eg, generalized lymphatic anomaly) is an abnormal proliferation of lymphatic endothelial cells. It is often a childhood disease, but it may present in adulthood by infiltrating organs and cause obstruction, bleeding, or disruption of lymphatic flow.
Laura J, Libby, Navneet, Narula, Helen, Fernandes, James F, Gruden, David J, Wolf, Daniel M, Libby   +5 more
openaire   +2 more sources

Pulmonary and pleural lymphatic endothelial cells from pediatric, but not adult, patients with Gorham-Stout disease and generalized lymphatic anomaly, show a high proliferation rate [PDF]

, 2016
Background: Gorham-Stout disease (OMIM 123880) and generalized lymphatic anomaly are two rare disorders of lymphendothelial growth in which thoracic involvement with chylothorax is a feared complication.
Mori, Michiko, Brodszki, Nicholas, Nicholas Brodszki, Erjefält, Jonas S., Erjefält, Jonas S, Beato, María, Erik A. Eklund, Eklund, Erik A, López-Gutiérrez, Juan Carlos, Jonas S. Erjefält, Juan Carlos López-Gutiérrez, Michiko Mori, Michael Dictor, Dictor, Michael, María Beato, Eklund, Erik A.   +15 more
core   +1 more source