Results 21 to 30 of about 1,017,855 (122)

Sirolimus in the treatment of kaposiform lymphangiomatosis

Orphanet Journal of Rare Diseases, 2021
Background Kaposiform lymphangiomatosis (KLA), which is a new subtype of generalized lymphatic anomaly, is a rare disease with a poor prognosis. Currently, there is no standard treatment due to the poor understanding of KLA.
Jiangyuan Zhou, Kaiying Yang, Siyuan Chen, Yi Ji   +3 more
doaj   +1 more source

Efficacy and safety of sirolimus treatment for intractable lymphatic anomalies: A study protocol for an open-label, single-arm, multicenter, prospective study (SILA)

Regenerative Therapy, 2019
Introduction: Lymphatic anomalies (LAs) refer to a group of diseases involving systemic dysplasia of lymphatic vessels. These lesions are classified as cystic lymphatic malformation (macrocystic, microcystic or mixed), generalized lymphatic anomaly, and ...
Michio Ozeki, Ryuta Asada, Akiko M. Saito, Hiroya Hashimoto, Takumi Fujimura, Tatsuo Kuroda, Shigeru Ueno, Shoji Watanabe, Shunsuke Nosaka, Mikiko Miyasaka, Akihiro Umezawa, Kentaro Matsuoka, Takanobu Maekawa, Yohei Yamada, Akihiro Fujino, Satoshi Hirakawa, Taizo Furukawa, Tatsuro Tajiri, Yoshiaki Kinoshita, Ryota Souzaki, Toshiyuki Fukao   +20 more
doaj   +1 more source

Lymphatic vascular morphogenesis in development, physiology, and disease [PDF]

, 2011
The lymphatic vasculature constitutes a highly specialized part of the vascular system that is essential for the maintenance of interstitial fluid balance, uptake of dietary fat, and immune response. Recently, there has been an increased awareness of the
Amélie Sabine, Petrova, T.V., Stefan Schulte-Merker, Sabine, A., Schulte-Merker, S., Petrova, T. V., Tatiana V. Petrova, Schulte-Merker, Stefan, Sabine, Amélie, Petrova, Tatiana V.   +9 more
core   +2 more sources

The impact of sirolimus therapy on lesion size, clinical symptoms, and quality of life of patients with lymphatic anomalies

Orphanet Journal of Rare Diseases, 2019
Background Lymphatic anomalies (LAs) include several disorders in which abnormal lymphatic tissue invades the neck, chest, and various organs. Progressive cases may result in lethal outcomes and have proven difficult to treat.
Michio Ozeki, Akifumi Nozawa, Shiho Yasue, Saori Endo, Ryuta Asada, Hiroya Hashimoto, Toshiyuki Fukao   +6 more
doaj   +1 more source

Personalized therapy for generalized lymphatic anomaly/Gorham-Stout disease with a combination of sunitinib and taxol

, 2015
The recently revised ISSVA classification approved in Melbourne in April 2014 recognizes generalized lymphatic anomaly and lymphatic malformation in Gorham-Stout disease.
Rößler, Jochen, Winterfeld, Moritz von, Saueressig, Ulrich, Klement, Gianoula L., Kayser, Gian   +4 more
core   +1 more source

Are we nearly there yet? Coverage and compliance of mass drug administration for lymphatic filariasis elimination. [PDF]

, 2015
Lymphatic filariasis has been targeted for elimination by 2020, and a threshold of 65% coverage of mass drug administration (MDA) has been adopted by the Global Programme to Eliminate Lymphatic Filariasis (GPELF).
Alexander, Neal DE
core   +1 more source

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

Andrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby, Sylvianne Hennebicq, Jacqueline Saias, Florence Brugnon, Isabelle Berthaut, Myriam Daudin, Louis Bujan, Ludovic Dumont, Christine Rondanino, Aurélie Feraille, Nathalie Rives   +10 more
wiley   +1 more source

Unmasking the invisible: Complex lymphatic anomaly uncovered by bilateral chylothorax

Rare
Complex lymphatic anomalies (CLA) are an extremely rare group of disorders resulting from embryogenic lymphatic malformations that are characterized by overlapping clinical, anatomic location, imaging features, and complications.
H. Ikrou, A. Ibenyahia, N. Boutbagha, M. Hachmi, M. Makloul, F. Ammor, I. lefquih, M. Maidi, S. Wakrim, O. Halloumi, S. Abdala, H. Serhane   +11 more
doaj   +1 more source

Prenatal imaging phenotypes and outcomes of umbilical‐portal‐systemic venous shunts in singleton and twin pregnancies: A historical cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
This retrospective cohort compared umbilical‐portal‐systemic venous shunts in singleton and twin pregnancies. Type III was the most common subtype in singletons, whereas Type II was the most common in twins. Fetal growth restriction was more frequent in twins, but primary structural anomaly rates were similar.
Yun Zhang, Meng Meng, Fengyu Wu, Jianping Chen, Fenhe Zhou, Yuchun Ge, Ya Xing, Xinyao Zhou, Gang Zou   +8 more
wiley   +1 more source

The Quality of Life Impact of Vascular Anomalies on Patients and Their Families: Experience of a Tertiary Australian Centre

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Chronic paediatric conditions often significantly impact the patients' and their families' quality of life (QoL). There is a paucity in the medical literature around the QoL impact of paediatric vascular anomalies on patients and their families in the Australian context. This study aims to address this gap.
Kwan Lam (Genevieve) Chow, Gloria Fong, Kelvin Truong, William Luu, Li‐Chuen Wong   +4 more
wiley   +1 more source