Results 181 to 190 of about 5,527,747 (326)

Skin-mimetic bilayer hydrogel enhances spatiotemporal coordination of neuro-immune-vascular interactions to accelerate diabetic wound healing. [PDF]

Bioact Mater
Wang H, Yang L, Jiang H, Li Z, Zhou X, Wang B, Zhang Z, Wang G, Chen S, He C.   +9 more
europepmc   +1 more source

Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis.

Carcinogenesis, 1997
R. Smits, A. Kartheuser, S. Jagmohan‐Changur, V. LeBlanc, C. Breukel, A. de Vries, H. V. van Kranen, J. H. Han van Krieken, S. Williamson, W. Edelmann, R. Kucherlapati, P. Meera Khan, Albert B. Einstein   +12 more
semanticscholar   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

Genetic differences in familial adenomatous polyposis syndrome in a Hungarian population: A prospective single center study. [PDF]

World J Gastroenterol
Tóth T, Bor R, Nagy D, Török D, Molnár T, Farkas K, Fábián A, Bősze Z, Bálint A, Bacsur P, Resál T, Szell M, Szepes Z.   +12 more
europepmc   +1 more source

Mutation analysis of the p53, APC, and p16 genes in the Barrett's oesophagus, dysplasia, and adenocarcinoma.

Journal of Clinical Pathology, 1997
María Verónica González, M. L. Artímez, L. Rodrigo, C. López-Larrea, M. Menéndez, V. Álvarez, R. Pérez, M. Fresno, M. Perez, A. Sampedro, E. Coto   +10 more
semanticscholar   +1 more source

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

Advanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao, Tong Xu, Chengyuan Wang, Chenyuan Wang, Junfeng Xie, Rui Zheng, Ke Wang, Xingzuo Jiang, Zewei Hu, Hongwei Jing, Lin Li, Tao Liu   +11 more
wiley   +1 more source

Single-immunocyte transcriptomics reveal the role of natural killer cell-dependent exogenous antigen presentation in ankylosing spondylitis severity. [PDF]

Exp Mol Med
Ke D, Dai H, Su Y, Zhu H, Liu X, Bai X, Zhang C, Xu J, Zhang J.   +8 more
europepmc   +1 more source

GNL3 Orchestrates AR Transcriptional Programs to Drive Castration‐Resistant Prostate Cancer and Immune Evasion

Advanced Science, EarlyView.
GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang, Tin Long Cheong, Nitin Narwade, Dandan Dong, Mokan Deng, Zhengqiang Miao, Zhaoqiang Ding, Wenchao Li, Kate Man Kei Lei, Gong‐Hong Wei, Terence Chuen Wai Poon, Chu‐Xia Deng, Edwin Cheung   +12 more
wiley   +1 more source

Common gene mutations in 103 authenticated colorectal cancer cell lines. [PDF]

Oncogenesis
Kranjec C, Eilertsen IA, Nunes L, Moosavi SH, Berg KCG, Eknæs M, Hektoen M, Niederdorfer B, Lind GE, Skotheim RI, Sveen A, Lothe RA.   +11 more
europepmc   +1 more source

Mutational Analysis of the CTNNB1 and APC Genes in Uterine Endometrioid Carcinoma

Modern Pathology, 2000
P. Schlosshauer, E. Pirog, R. Levine, L. H. Ellenson   +3 more
semanticscholar   +1 more source