Results 251 to 260 of about 243,880 (305)

Learning from plants: is it possible to make an animal organism a non-host for cancer? [PDF]

Front Oncol
Nemchinov LG.
europepmc   +1 more source

A set cover algorithm identifies minimal circulating tumour DNA sequencing targets for colorectal cancer detection. [PDF]

Sci Rep
Moloney-Geany K, Black MA, Day RC, Guilford P, Dunnet MJ.   +4 more
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Ubiquitin-Mediated Proteolysis as a Regulator of the Plant Defense-Growth Balance. [PDF]

Plants (Basel)
Gonçalves MF, Carneiro AK, Otero RM, Hemerly AS.   +3 more
europepmc   +1 more source

Early mutational events and clonal dynamics in normal crypts: implications for colorectal tumorigenesis. [PDF]

Hum Genomics
Marvalim C, Chan DKH.
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Mechanisms Underlying Cancer Chemoresistance: A Starting Point to Identify New Anticancer Strategies. [PDF]

Int J Mol Sci
Domenicotti C, Marengo B.
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COX-2 regulates IL-17A-producing γδ T cells to drive mismatch repair-deficient colon cancer

Suzuki T, White M, Leach J, Edwards J, Gilroy K, Porter R, Hong Y, Terradas-Terradas M, Hayman H, Mohamed NE, Lannagan T, Mackey J, Ridgway R, Campbell A, Verbandt S, Kirschner K, Tejpar S, Edwards J, Dunne P, Coffelt S, Sansom O.   +20 more
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The Many Faces of the Tumor Suppressor Gene APC

Experimental Cell Research, 2001
Inactivation of the tumor suppressor adenomatous polyposis coli (APC) protein is a critical early step in the development of familial and sporadic colon cancer. Close examination of the function of APC has shown that it is a multifunctional protein involved in a wide variety of processes, including regulation of cell proliferation, cell migration, cell
Es, J.H. van, Giles, R.H., Clevers, J.C.
openaire   +3 more sources

The APC gene in colorectal cancer

European Journal of Cancer, 2002
Mutations in the adenomatous polyposis coli (APC) gene are not only responsible for familial adenomatous polyposis (FAP), but also play a rate-limiting role in the majority of sporadic colorectal cancers. Colorectal tumours are known to arise through a gradual series of histological changes, the so-called 'adenoma-carcinoma' sequence, each accompanied ...
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The I1307K polymorphism of the APC gene in colorectal cancer

Gastroenterology, 1999
Colorectal cancer is one of the most frequent cancers in humans. Recently, a germline missense mutation, I1307K, was identified in the adenomatous polyposis coli (APC) gene that was suggested to increase cancer predisposition in Ashkenazi Jews. However, a second study indicated that the I1307K mutation did not contribute greatly to the risk of colon ...
Prior TW, Chadwick RB, Papp AC, Arcot AN, Isa AM, Pearl DK, Stemmermann G, PERCESEPE, Antonio, Loukola A, Aaltonen LA, de la Chapelle A.   +10 more
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