High Prevalence of Non-BRCA Pathogenic Variants and a Recurrent PALB2 Variant in an Argentine Hereditary Breast and Ovarian Cancer Cohort. [PDF]
Martin CA +10 more
europepmc +1 more source
Decoding the Oncogenic Role of USP22 Through Pan‐Cancer Genomic and Epigenetic Analysis
ABSTRACT Background Ubiquitin‐specific protease 22, an important catalytic component of the human SAGA (Spt‐Ada‐GcN5 Acetyltransferase) complex, regulates the deubiquitination and methylation of histones, which in turn influences gene expression. Its overexpression alters gene regulation, transcription, cancer progression, and therapy resistance.
Uma Devi A., Prakash Kumar Shukla
wiley +1 more source
Gene Expression Profiles Associated with Molecular Subtypes and Pathological Response to Neoadjuvant Treatment in Surgical Breast Cancer. [PDF]
Baulies S +7 more
europepmc +1 more source
Patenting the Fingerprint of God: How Gene Patents Violate the Products of Nature Doctrine [PDF]
Todd, Timothy M.
core +1 more source
• XPO1 hyperactivation promotes leukaemogenesis by altering nucleocytoplasmic transport and transcriptional control in acute myeloid leukaemia (AML). • Selinexor and eltanexor show preferential activity in NPM1‐mutated, DEK::NUP214‐positive and SF3B1‐mutated myeloid neoplasms.
Yifan Liu +4 more
wiley +1 more source
National survey of urologists' views on prostate cancer screening in the United Kingdom
BJUI Compass, Volume 7, Issue 5, May 2026.
Nikhil Mayor +5 more
wiley +1 more source
Integrated workflow of domoic acid (DA) detection in seafood using a high‐sensitivity electrochemical biosensor and subsequent evaluation of DA‐induced cellular responses. (A) DA monitoring in seafood: Marine samples (European anchovy and mussels from the Marmara and Black Sea) were collected, extracted using a 1:1 methanol/water mixture, and analyzed ...
Emilia Qomi Ekenel +10 more
wiley +1 more source
Identification of Genetic Variants Among Breast Cancer Patients and At-Risk Individuals: A Cohort Study in Sri Lanka. [PDF]
Yatawara L +4 more
europepmc +1 more source
ABSTRACT Background and Aims Breast cancer is the most common cancer among women worldwide. This study aimed to determine the frequency of breast cancer molecular subtypes and the associations of ER, PR, and HER2 status with demographic, reproductive, hormonal, and cancer stage in Qazvin, Iran (2021–2023).
Ensiyeh Bahadoran +4 more
wiley +1 more source
BRCA1/2 and CHEK2 Pathogenic Variants in Urological Cancers: A Portuguese Single-Center Experience. [PDF]
Quinto Pereira M +7 more
europepmc +1 more source

