Results 181 to 190 of about 44,727 (269)

Breast cancer risk genes affecting individual radiosensitivity. [PDF]

Sci Rep
Vogel RKG, Amann N, Kassem TZ, Gaß P, Mayo T, Woltereck F, Hack CC, Fietkau R, Corradini S, Distel L, Kuhlmann LCF.   +10 more
europepmc   +1 more source

Frame-shift mutations in BRCA1 and BRCA2 genes in Turkish families with breast and/or ovarian cancer

, 2010
It is well established that mutations in BRCA1 and BRCA2 genes significantly increase the risk of breast and/or ovarian cancer. Notably frame-shift mutations of BRCA1 and BRCA2 genes were linked to high risk.
Urbano, K. V.
core  

Germline BRCA2 mutations foster resistance to CDK4/6 inhibitors in breast cancer. [PDF]

NPJ Precis Oncol
Bolini L, Naulin F, Johnson N, Galluzzi L.   +3 more
europepmc   +1 more source

Double jeopardy: how <i>BRCA2</i>, <i>TP53</i>, and <i>DNMT3A</i> redefine the link between infertility and cancer risk. [PDF]

Front Cell Dev Biol
Huang Z, Abbas M, Hussain A, Long M, Muzammal M, Song K.   +5 more
europepmc   +1 more source

MOLECULAR BASIS OF BREAST CANCER RELATED TO BRCA 1 AND BRCA2 GENES: CHARACTERISTICS AND TARGETING THERAPY

, 2010
Rak dojke je jedan od najčešćih tumora u žena, koji u sebi nosi i značajnu komponentu obiteljske sklonosti bolesti u kojoj geni BRCA1 i BRCA2 imaju veliku ulogu.
LEVANAT, SONJA, LEVAČIĆ CVOK, Mirela, SONJA LEVANAT, Mirela LEVAČIĆ CVOK   +3 more
core  

Prevalence and clinical significance of germline pathogenic variants identified by multigene panel testing in high-risk Japanese patients with breast cancer. [PDF]

Breast Cancer
Kano M, Taruno K, Inuzuka M, Makino R, Takeuchi M, Suzuki M, Kida K, Takei J, Nagayama A, Hayashida T, Haruyama Y, Ueno T, Watanabe C, Kojima Y, Sasai R, Endo M, Momozawa Y, Nakamura S.   +17 more
europepmc   +1 more source

From Germline Susceptibility to Therapeutic Vulnerability: DNA Damage Response Gene Mutations Driving Multiple Myeloma Evolution and Precision Therapy. [PDF]

Hum Mutat
Shen Q, Wang Y, Cai L, Qian J.
europepmc   +1 more source

From mutation to treatment: The dual role of BRCA1 and BRCA2 in gynecological malignancy development and management a systematic review. [PDF]

Biochem Biophys Rep
Georgy DM, Sedeek HN, Abaza NE, Eldeeb SEK, Khamis SM, Elgamil MR, Magar RW.   +6 more
europepmc   +1 more source

Germline Pathogenic Variants in Homologous Recombination Pathway Genes Are Frequent in Pancreatobiliary Ampullary Carcinoma. [PDF]

JCO Precis Oncol
Misyura M, Selenica P, Ozcan K, Kemel Y, Basturk O, O'Reilly EM, Reis-Filho JS, Beets-Tan R, Stadler ZK, Weigelt B, Mandelker D.   +10 more
europepmc   +1 more source

BRCA1/2 Reversion Mutations and Cancer Therapy Resistance. [PDF]

Biology (Basel)
Qi W, Yang G, Zhang Y, Han L, Mayo KH, Zeng X, Mo J.   +6 more
europepmc   +1 more source