Results 121 to 130 of about 71,732 (246)

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Identification of key genes associated with muscle atrophy after spinal cord injury and experimental verification in rats. [PDF]

Front Immunol
Wang X, Gao Y, Huo J.
europepmc   +1 more source

Current Advancements of Probiotic Foods and Their Role in Sustainable Food Security

Food Bioengineering, EarlyView.
ABSTRACT Probiotic foods have evolved from traditional fermented products to scientifically validated functional foods, defined by the FAO and WHO as live microorganism that confer a health benefit on the host when administered in adequate amounts, with effects being strain, does and end point specific.
Ashenafi Teklay Yaekob, Gebremedhin Gebreslassie, Etsay Mesele, Tesfakiros Semere   +3 more
wiley   +1 more source

Early-life microbiota disruption-induced deficits in the social brain are sensitive to diet. [PDF]

iScience
Ratsika A, Bergmann CA, Valderrama B, Bastiaanssen TFS, Sharvin BL, Renes IB, Knol J, Gunnigle E, Clarke G, Cryan JF.   +9 more
europepmc   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Mechanistic insights into Shenqi Dihuang decoction in the treatment of immunoglobulin a nephropathy. [PDF]

Front Pharmacol
Gao Y, Pang X, Li D, Chen X, Li D, Chen Z.   +5 more
europepmc   +1 more source

Neoarchean Arc Magmatism and Crust Recycling in the Northern Marginal Zone of the Limpopo Complex, Zimbabwe: New Insights From Zircon U‐Pb‐Hf Isotopes of a Charnockite Suite

Geological Journal, EarlyView.
Charnockites with 2691–2607 Ma magmatic ages from the NMZ show arc‐magmatic geochemical signatures. They correspond to the lower‐crustal equivalent of the Chilimanzi Suite Granite in the Zimbabwe Craton. Lu‐Hf isotopic data of magmatic zircons show negative εHf(t) values (−11.18 to −2.20) with TDMC ages of 3699–3158 Ma, suggesting their protolith ...
Toshiaki Tsunogae, Md. Sazzadur Rahman, Gao Pin, M. Santosh, Wataru Fujisaki, Sam Uthup, Prince Mandingaisa   +6 more
wiley   +1 more source

A stage specific NETs-related signature in alcoholic steatohepatitis: from molecular subtyping to therapeutic vulnerabilities. [PDF]

Front Immunol
Gao W, Lin Z, Bao Y, Liu M, Ma G, Chen X, Yu S, Zeng Y.   +7 more
europepmc   +1 more source