Results 131 to 140 of about 71,732 (246)

Exploring the Potential Roles of Oxidative Stress-Related Genes in Thyroid Eye Disease and Graves' Disease. [PDF]

J Ophthalmol
Zhang W, Huang Q, Jinying Li.
europepmc   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice. [PDF]

Nat Commun
Cuesta-Marti C, Ponce-España E, Uhlig F, Stoltenborg I, Wasiewska LA, Kareem L, Hedayatpour D, Olavarría-Ramírez L, Rosell-Cardona C, Bastiaanssen TFS, Tofani GSS, Valderrama B, Vlckova K, Dickson SL, Lavelle A, Stanton C, Ross RP, Cryan JF, Dinan TG, Clarke G, O'Mahony SM, Schellekens H.   +21 more
europepmc   +1 more source

Tumor‐Intrinsic Forkhead Box A2 Regulates the Lymph Node Metastasis of Papillary Thyroid Carcinoma by Regulating T‐Cell Apoptosis

iLABMED, EarlyView.
We identified FOXA2 as a key regulator of lymph node metastasis in thyroid cancer, which controls cancer cell aggressiveness. FOXA2 knockdown promotes metastasis by enhancing tumor cell migration and, importantly, by inducing T‐cell apoptosis through a CCL2/LCN2‐mediated pathway. Created with BioGDP.com.
Ping Yang, Xueying Zhang, Wen Deng, Fangning Gao, Shujia Peng, Guoqiang Bao, Lijuan Yuan   +6 more
wiley   +1 more source

Truncated FOS impairs osteogenic differentiation and induces prostaglandin and NFκB signalling in an in vitro cell-of-origin model for osteoid osteoma and osteoblastoma. [PDF]

J Pathol
Lam SW, Belova T, Franceschini N, van den Akker B, van IJzendoorn DG, Mikkers HM, Mei H, Cleton-Jansen AM, Kuijjer ML, Szuhai K, Bovée JV.   +10 more
europepmc   +1 more source

Chromatin unwinding state for in situ identification and lineage tracing of circulating tumor cells

iMeta, EarlyView.
The detection of circulating tumor cells (CTCs) through liquid biopsy offers a non‐invasive approach for accurately monitoring cancer dissemination and evaluating therapeutic efficiency. However, their rarity and heterogeneity limit conventional tumor antigen labelling‐based methods in identifying and tracing CTCs.
Bin Ye, Zhen Wang, Yinqi Bai, Xu Zhang, Rui Zhang, Jingru Lian, Xuefei Liu, Yan Zhang, Zhiyuan Xu, Li Yang, Haiman Jin, Fang Chen, Zhihao Xie, Ping Zhou, Jun Tan, Shan Zeng, Changzheng Du, Yang Min, Xiaomin Ni, Jingxian Duan, Zhicheng Li, Hui Yang, Yunpeng Cai, Hongyan Wu, Catherine C. Liu, Jing Cai, Yi Lu, Jian Zhang, Hao Wu, Hairong Zheng, Longqi Liu, Xin Hong, Hao Yu   +32 more
wiley   +1 more source

Integrative network toxicology and experimental evidence reveal mechanisms underlying diethyl phthalate-induced initiation and progression of endometrial cancer. [PDF]

Sci Rep
Chen X, Wang Z, Wang F, Wu Y, Hu D, Cheng Y, Xing Y, Du J, Jiang T, Yang Y, Liang X, Bi X.   +11 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

GSTA1 deficiency drives neuroendocrine differentiation via TNFRSF13B/c-FOS/CHGA axis in prostate cancer. [PDF]

Int J Biol Sci
Qian J, Luo Y, Fu Y, Diao W, Ding Q, Chen W, Qiu X, Guo H.   +7 more
europepmc   +1 more source

Sequential ultrasound‐driven dynamic control of macrophage polarization combined with hydrogel for mechano‐chemical synergistic tissue repair

Interdisciplinary Medicine, EarlyView.
This study presents an innovative therapeutic strategy that integrates sequential ultrasound therapy with an injectable oxidized dextran‐metformin (ODE‐Met) hydrogel to dynamically regulate macrophage polarization and promote angiogenesis for inflamed tissue repair.
Fulong Man, Kun Wang, Zichen Yang, Lulu An, Caoyi You, Rongjie Li, Yanni Cai, Yang Li, Li Chen, Yiqiong Liu, Yan Li, Haiqing Dong, Yongyong Li   +12 more
wiley   +1 more source