Results 1 to 10 of about 24,940 (176)

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]

PLoS Pathogens, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
Jessica C Jang, Gang Chen, Spencer H Wang, Mark A Barnes, Josiah I Chung, Mali Camberis, Graham Le Gros, Philip J Cooper, Cathy Steel, Thomas B Nutman, Mitchell A Lazar, Meera G Nair   +11 more
doaj   +23 more sources

Sensitive and accurate DNA metabarcoding of parasitic helminth mock communities using the mitochondrial rRNA genes

Scientific Reports, 2022
Next-generation sequencing technologies have accelerated the pace of helminth DNA metabarcoding research, enabling species detection in bulk community samples.
Abigail Hui En Chan, Naowarat Saralamba, Sompob Saralamba, Jiraporn Ruangsittichai, Kittipong Chaisiri, Yanin Limpanont, Vachirapong Charoennitiwat, Urusa Thaenkham   +7 more
doaj   +4 more sources

Widespread gene fusion artifacts in helminth genome annotations [PDF]

BMC Genomics
Background Current helminth genomes possess thousands of predicted fusion genes, encoding novel protein domain architectures that are unique to these species.
Emma L. Collington, Andrew C. Doxey, Brendan J. McConkey, D. Moira Glerum   +3 more
doaj   +2 more sources

Intestinal helminth Schyzocotyle acheilognathi Yamaguti, 1934 infection ameliorate lipid metabolism of grass carp (Ctenopharyngodon idella) through immune and gut microbiota regulation [PDF]

Frontiers in Microbiology
Fats have been widely applied in aquaculture to promote growth performance and substitute partial protein in fish feeds. However, excessive dietary fat levels induce metabolic disorders harming the health of cultured fish.
Xiaoao Yang, Denghui Zhu, Wenxiang Li, Peipei Fu   +3 more
doaj   +2 more sources

Investigating the development of diarrhoea through gene expression analysis in sheep genetically resistant to gastrointestinal helminth infection [PDF]

Scientific Reports, 2022
Gastrointestinal helminths infect livestock causing health problems including severe diarrhoea. To explore the underlying biological mechanisms relating to development and control of diarrhoea, we compared 4 sheep that were susceptible to development of ...
Shamshad Ul Hassan, Eng Guan Chua, Erwin A. Paz, Parwinder Kaur, Chin Yen Tay, Johan C. Greeff, Shimin Liu, Graeme B. Martin   +7 more
doaj   +3 more sources

Association study in naturally infected helminth layers shows evidence for influence of interferon-gamma gene variants on Ascaridia galli worm burden [PDF]

Veterinary Research, 2011
Single nucleotide polymorphisms (SNPs) in the genes for interleukin-4, -13 and interferon-gamma, and 21 additional SNPs which previously had been significantly associated with immune traits in the chicken, were genotyped in white and brown layer hens and
Lühken Gesine, Gauly Matthias, Kaufmann Falko, Erhardt Georg   +3 more
doaj   +4 more sources

Delineating markers of disease-disease interaction: a systematic methodology and its application to multiple diabetes-helminth cohorts [PDF]

BMC Bioinformatics
Background Understanding how the molecules in our bodyrespond to the co-occurrence of two diseases in an individual (comorbidity) could lead tomechanistic insights into novel treatments for comorbid conditions.
Nilesh Subramanian, Philge Philip, Anuradha Rajamanickam, Nathella Pavan Kumar, Subash Babu, Manikandan Narayanan   +5 more
doaj   +2 more sources

Hookworm infection modulates lung and intestinal transcriptomic responses to SARS-CoV-2 in Syrian hamsters [PDF]

Frontiers in Immunology
BackgroundHelminth infections are widespread in resource-limited settings, and modulate host immune responses, with potential implications for viral coinfections.
Bruce A. Rosa, Mahdiyeh Bigham, Tamarand L. Darling, Ashutosh Arun, Kumar Sachin Singh, John Martin, Adrianus C. M. Boon, Adrianus C. M. Boon, Adrianus C. M. Boon, Makedonka Mitreva, Makedonka Mitreva, Makedonka Mitreva   +11 more
doaj   +2 more sources

Genetics of helminth infections: Immune system response, insights into host-parasite interaction, and drug resistance [PDF]

Journal of Advanced Veterinary and Animal Research
Helminthiases, which are caused by parasitic helminths, have a big effect on global health, especially in places with few resources. They cause a lot of illness and put a lot of strain on society and the economy.
Mashael Abdullah Aldamigh
doaj   +2 more sources

Comparative transcriptomics of stickleback immune gene responses upon infection by two helminth parasites, Diplostomum pseudospathaceum and Schistocephalus solidus [PDF]

Zoology, 2016
Immune systems of vertebrates are much more diverse than previously thought, in particular at the base of the vertebrate clade. RNA-seq was used to describe in detail the transcriptomic response of stickleback hosts to infection by two helminth parasites,
Bornberg-Bauer, Erich, Haase, David, Kalbe, Martin, Reusch, Thorsten B.H., Rieger, Jennifer K., Scharsack, Jörn P., Schmidt-Drewello, Alexander, Stoll, Monika, Witten, Anika   +8 more
core   +5 more sources