Results 31 to 40 of about 23,322 (214)

Promoter haplotypes of the interleukin-10 gene influence proliferation of peripheral blood cells in response to helminth antigen [PDF]

Genes & Immunity, 2004
Since interleukin (IL)-10 is a key mediator of immunosuppression, and immunosuppression is considered an important element of helminth infection, we studied variants of the putative IL-10 gene promoter in 337 individuals from 130 families heavily exposed to infection by the tissue nematode Onchocerca volvulus.
Bertram Müller-Myhsok, Bertram Müller-Myhsok, Thorsten Thye, S Fuchs, Jürgen Sievertsen, Christian Timmann, Rolf D. Horstmann, Norbert W. Brattig, B. Lepping, C Thoma   +9 more
openaire   +3 more sources

Gene expression patterns during adaptation of a helminth parasite to different environmental niches [PDF]

Genome Biology, 2007
Abstract Background Schistosome bloodflukes are complex trematodes responsible for 200 million cases of schistosomiasis worldwide. Their life cycle is characterized by a series of remarkable morphological and biochemical transitions between an invertebrate host, an aquatic environment, and a mammalian ...
Emmitt R. Jolly, Chen-Shan Chin, Steve Miller, Mahmoud Mohamed Bahgat, K. C. Lim, Joseph L. DeRisi, James H. McKerrow   +6 more
openaire   +5 more sources

Relationship between NRAMP1 gene polymorphism and efficacy of BCG vaccine in helminth-infected populations

Genetics and Molecular Research, 2013
Infection of mothers with schistosomiasis and filariasis has been shown to influence infant responses to neonatal Bacille Calmette-Guérin (BCG) immunization. The genetic makeup of infants is also considered an important determinant for the activity of BCG vaccine.
Nadeem A. Kizilbash, Soha I. Awad, Abdelnaser Badawy, Raida S. Yahya, G. A. Al-Sawah   +4 more
openaire   +3 more sources

Single-Nucleotide Polymorphisms in the Beta-Tubulin Gene and Its Relationship with Treatment Response to Albendazole in Human Soil-Transmitted Helminths in Southern Mozambique

The American Journal of Tropical Medicine and Hygiene, 2022
ABSTRACT. Soil-transmitted helminth (STH) cornerstone control strategy is mass drug administration (MDA) with benzimidazoles. However, MDA might contribute to selection pressure for anthelmintic resistance, as occurred in livestock. The aim of this study is to evaluate the treatment response to albendazole and the relationship with the presence of ...
Grau-Pujol, B., Gandasegui, J., Escola, V., Marti-Soler, H., Cambra-Pelleja, M., Demontis, M., Brienen, E.A.T., Jamine, J.C., Muchisse, O., Cossa, A., Sacoor, C., Cano, J., Lieshout, L. van, Martinez-Valladares, M., Munoz, J.   +14 more
openaire   +5 more sources

Placental gene expression and antibody levels of mother-neonate pairs reveal an enhanced risk for inflammation in a helminth endemic country [PDF]

Scientific Reports, 2019
AbstractIn uteroexposure to environmental factors can modify the development of allergies later in life whereby the mechanisms of the feto-maternal crosstalk still remain largely unknown. Murine studies revealed that inflammatory maternal signals elicited by chronic helminth infection within the placenta imprint a distinct gene expression profile ...
Ludwig, E., Harder, J., Lacorcia, M., Honkpehedji, Y.J., Nouatin, O.P., Dam, G.J. van, Corstjens, P.L.A.M., Sartono, E., Esen, M., Lobmaier, S.M., Adegnika, A.A., Costa, C.P. da   +11 more
openaire   +4 more sources

Mmp17-deficient mice exhibit heightened goblet cell effector expression in the colon and increased resistance to chronic Trichuris muris infection

Frontiers in Immunology, 2023
Intestinal epithelial homeostasis is maintained by intrinsic and extrinsic signals. The extrinsic signals include those provided by mesenchymal cell populations that surround intestinal crypts and is further facilitated by the extracellular matrix (ECM),
Pia M. Vornewald, Ruth Forman, Rouan Yao, Naveen Parmar, Håvard T. Lindholm, Lilith S. K. Lee, Mara Martín-Alonso, Kathryn J. Else, Menno J. Oudhoff, Menno J. Oudhoff   +9 more
doaj   +1 more source

The Immune and Non-Immune Pathways That Drive Chronic Gastrointestinal Helminth Burdens in the Wild

Frontiers in Immunology, 2018
Parasitic helminths are extremely resilient in their ability to maintain chronic infection burdens despite (or maybe because of) their hosts’ immune response.
Simon A. Babayan, Wei Liu, Graham Hamilton, Elizabeth Kilbride, Evelyn C. Rynkiewicz, Melanie Clerc, Amy B. Pedersen   +6 more
doaj   +1 more source

Author Correction: Placental gene expression and antibody levels of mother-neonate pairs reveal an enhanced risk for inflammation in a helminth endemic country [PDF]

Scientific Reports, 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Meral Esen, Silvia M. Lobmaier, Paul L. A. M. Corstjens, Yabo Josiane Honkpehedji, Clarissa Prazeres da Costa, Govert J. van Dam, Esther Ludwig, Ayola A. Adegnika, Matthew Lacorcia, Odilon Nouatin, Erliyani Sartono, Jutta Harder   +11 more
openaire   +2 more sources

The host immune response to gastrointestinal nematode infection in sheep [PDF]

, 2015
non peer reviewedGastrointestinal nematode infection represents a major threat to the health, welfare and productivity of sheep populations worldwide. Infected lambs have a reduced ability to absorb nutrients from the gastrointestinal tract, resulting in
Abraham, Ahmed, Akiho, Amarante, Andronicos, Anthony, Balic, Balic, Balic, Balic, Becattini, Beraldi, Bishop, Bisset, Bisset, Bowdridge, Brunsdon, Brunsdon, Brunsdon, Buddle, Cardia, Clarke, Conway, Coop, Craig, Craig, Crespo, Dawicki, Deplancke, deSchoolmeester, Diez-Tascon, Donaldson, Douch, Douch, Dunsmore, Else, Finkelman, Finkelman, Finney, French, Fuhrman, Geijtenbeek, Gilfillan, Gill, Glass, Gossner, Gossner, Grainger, Halliday, Hansen, Harriman, Harrison, Harrison, Hassan, Hassan, Henderson, Hogan, Houdijk, Hsieh, Huntley, Huntley, Huntley, Ingham, Khan, Kim, Kooyman, Korn, Lacroux, Lazarevic, Lighvani, MacKinnon, Madden, Malan, Mantovani, Marson, McClure, McGuckin, McKenna, McRae, McSorley, Meeusen, Mori, Nair, Ohkura, Paul, Pernthaner, Pernthaner, Pettit, Rainbird, Rosenberg, Sangster, Scott, Seaton, Shakya, Shaw, Shaw, Smith, Smith, Stear, Stear, Stear, Stear, Stevenson, Stone, Strain, Sutherland, Szabo, Taylor, Terefe, Urb, Vallance, Vignali, Voehringer, Williams   +113 more
core   +1 more source

Genetic parameters of infectious bovine keratoconjunctivitis and its relationship with weight and parasite infestations in Australian tropical Bos taurus cattle

Genetics Selection Evolution, 2012
Background Infectious bovine keratoconjunctivitis (IBK) or ‘pinkeye’ is an economically important ocular disease that significantly impacts animal performance.
Ali Abdirahman A, O’Neill Christopher J, Thomson Peter C, Kadarmideen Haja N   +3 more
doaj   +1 more source