Molecular helminthology in the Rockies [PDF]
A report on the Keystone Symposium on Molecular Helminthology, Copper Mountain, Colorado, USA, 9-13 April ...
Blaxter, M.
core +2 more sources
Enteric helminths promote Salmonella co-infection by altering the intestinal metabolome [PDF]
Intestinal helminth infections occur pre dominantly in regions where exposure to enteric bacterial pathogens is also common. Helminth infections inhibit host immunity against microbial pathogens, which has largely been attributed to the induction of ...
Borchers, Christoph H. +13 more
core +1 more source
Haemonchus contortus P-glycoproteins interact with host eosinophil granules: a novel insight into the role of ABC transporters in host-parasite interaction. [PDF]
Eosinophils are one of the major mammalian effector cells encountered by helminths during infection. In the present study, we investigated the effects of eosinophil granule exposure on the sheep parasitic nematode Haemonchus contortus as a model.
Mohamed Issouf +8 more
doaj +1 more source
Recombinant expression systems: the obstacle to helminth vaccines? [PDF]
A
Claerebout, Edwin +3 more
core +2 more sources
Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. [PDF]
Immunophilin is the collective name given to the cyclophilin and FK506-binding protein (FKBP) families. As the name suggests, these include the major binding proteins of certain immunosuppressive drugs: cyclophilins for the cyclic peptide cyclosporin A ...
Adams +101 more
core +1 more source
Effect of heterogeneous mixing and vaccination on the dynamics of anthelmintic resistance: a nested model. [PDF]
Anthelmintic resistance is a major threat to current measures for helminth control in humans and animals. The introduction of anthelmintic vaccines, as a complement to or replacement for drug treatments, has been advocated as a preventive measure.
Lorenzo Sabatelli
doaj +1 more source
Temporal Changes in Total Serum Immunoglobulin E Levels in East German Children and the Effect of Potential Predictors [PDF]
Background: Elevated total serum immunoglobulin E (IgE) levels are a prominent feature of allergic and parasitic diseases. An epidemiologic study was conducted in East German children to describe trends in the development of total serum IgE levels and ...
Brüske, Irene +5 more
core +1 more source
Symbiont microbial communities play important roles in animal biology and are thus considered integral components of metazoan organisms, including parasitic worms (helminths). Nevertheless, the study of helminth microbiomes has thus far been largely overlooked, and symbiotic relationships between helminths and their microbiomes have been only ...
Formenti, Fabio +3 more
openaire +3 more sources
A role for peroxisome proliferator-activated receptors in the immunopathology of schistosomiasis? [PDF]
Peroxisome proliferator-activated receptors (PPARs) have been demonstrated to have a role in immune regulation. In general, they are anti-inflammatory and promote Th2 type responses, and they are associated with the alternative activation of macrophages.
Allen, JT +3 more
core +4 more sources
The Immune and Non-Immune Pathways That Drive Chronic Gastrointestinal Helminth Burdens in the Wild
Parasitic helminths are extremely resilient in their ability to maintain chronic infection burdens despite (or maybe because of) their hosts’ immune response.
Simon A. Babayan +6 more
doaj +1 more source

