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Homeobox genes and gut development
BioEssays, 2000The gut of vertebrates exhibits a common anteroposterior regional differentiation. The role of homeobox genes in establishing this pattern is inferred by their sites of expression. It is suggested that the primary source of positional information is in the endoderm, which subsequently establishes a 'dialogue' with the surrounding visceral layer of the ...
Beck, F, Tata, F, Chawengsaksophak, K
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HOMEOTIC GENES AND THE HOMEOBOX
Annual Review of Genetics, 1986INTRODUCTION ...... 147 PHENOTYPIC EFFECTS OF HOMEOTIC MUTATIONS . .. ....... 149 GENETIC AND MOLECULAR ORGANIZATION ..... 154 The Antennapedia Complex . . 154 The Bithorax Complex . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157 THE HOMEOBOX . . .. ...... .
W J, Gehring, Y, Hiromi
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Duplicated homeobox genes in Xenopus
Developmental Biology, 1989Multiple kinds of clones and restriction fragment polymorphisms are frequently encountered when analyzing genes of the tetraploid frog Xenopus laevis. Two types of cDNA clone have been isolated for homeobox gene 2. Analysis of their corresponding genomic clones confirmed the existence of clearly distinct restriction maps; in addition the nearby ...
A F, Fritz +4 more
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Homeobox genes and the zootype
Nature, 1993This Article does not have an ...
Miller, David, Miles, Annabel
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Biochemical Genetics, 1994
We report the isolation of nine rat cognates of mouse homeoboxes within the four Hox gene clusters and a rat homologue of mouse IPF1 homeobox, RHbox#13A. The sequences of nine cloned homeoboxes are highly similar to those of the mouse and human homeoboxes in the Hox clusters. The restriction enzyme sites and map distances between each of the homeoboxes
Y, Sakoyama +3 more
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We report the isolation of nine rat cognates of mouse homeoboxes within the four Hox gene clusters and a rat homologue of mouse IPF1 homeobox, RHbox#13A. The sequences of nine cloned homeoboxes are highly similar to those of the mouse and human homeoboxes in the Hox clusters. The restriction enzyme sites and map distances between each of the homeoboxes
Y, Sakoyama +3 more
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Homeobox genes and the specification of neuronal identity
Nature Reviews Neuroscience, 2021O. Hobert
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Homeobox Genes and Orofacial Development
Connective Tissue Research, 1995The discovery of the homeobox as a highly conserved DNA-binding motif found in homeotic and other genes involved in the control of Drosophila development has dramatically changed developmental biology. It has now become clear that whereas morphologically Drosophila and mammalian embryos develop very differently, the genetic control of their development
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Homeobox genes in Caenorhabditis elegans
Current Opinion in Genetics & Development, 1993It is estimated that approximately 60 homeobox genes occur in the nematode Caenorhabditis elegans. These genes are required for specifying the cell fate of both precursor and terminally differentiated cells. In some cases, highly specific cell functions, such as migration pattern or synaptic connectivity, require the action of these genes.
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Organization of human homeobox genes
Human Reproduction, 1988The chromosomal localization of 17 human homeoboxes and the predicted primary sequence of the encoded homeodomains is reported. These homeoboxes are clustered in four complex HOX loci on chromosomes 2, 7, 12 and 17. Although the identification of human homeoboxes has not been completed, existing data permit preliminary conclusions on the origin and ...
Edoardo Boncinelli +6 more
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Homeobox genes and heart development
Trends in Cardiovascular Medicine, 1995Genes encoding transcription factors are fundamental to developmental processes because their DNA-binding proteins can control expression of a multitude of genes. Therefore, activation of a single transcription factor gene can act as a genetic switch that controls the developmental destinies of groups of cells.
M J, Kern, E A, Argao, S S, Potter
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