Results 211 to 220 of about 73,647 (262)
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Homeobox Genes and Orofacial Development
Connective Tissue Research, 1995The discovery of the homeobox as a highly conserved DNA-binding motif found in homeotic and other genes involved in the control of Drosophila development has dramatically changed developmental biology. It has now become clear that whereas morphologically Drosophila and mammalian embryos develop very differently, the genetic control of their development
Paul Sharpe
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Homeobox genes and the zootype
Nature, 1993This Article does not have an ...
Miller, David, Miles, Annabel
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HOMEOTIC GENES AND THE HOMEOBOX
Annual Review of Genetics, 1986INTRODUCTION ...... 147 PHENOTYPIC EFFECTS OF HOMEOTIC MUTATIONS . .. ....... 149 GENETIC AND MOLECULAR ORGANIZATION ..... 154 The Antennapedia Complex . . 154 The Bithorax Complex . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157 THE HOMEOBOX . . .. ...... .
W J, Gehring, Y, Hiromi
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Genetica, 1994
In the former part of the review the principal available data about Hox genes, their molecular organisation and their expression in vertebrate embryos, with particular emphasis for mammals, are briefly summarized. In the latter part we analysed the expression of four mouse homeobox genes related to two Drosophila genes expressed in the developing head ...
Boncinelli E., Mallamaci A., Lavorgna G.
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In the former part of the review the principal available data about Hox genes, their molecular organisation and their expression in vertebrate embryos, with particular emphasis for mammals, are briefly summarized. In the latter part we analysed the expression of four mouse homeobox genes related to two Drosophila genes expressed in the developing head ...
Boncinelli E., Mallamaci A., Lavorgna G.
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Experimental Cell Research, 1999
Homeobox-containing genes are a family of regulatory genes encoding transcription factors that primarily play a crucial role during development. Several indications suggest their involvement in the control of cell growth and, when dysregulated, in oncogenesis.
CILLO, CLEMENTE +3 more
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Homeobox-containing genes are a family of regulatory genes encoding transcription factors that primarily play a crucial role during development. Several indications suggest their involvement in the control of cell growth and, when dysregulated, in oncogenesis.
CILLO, CLEMENTE +3 more
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Current Biology, 1991
Recent highlights in vertebrate homeobox gene research include the discovery of new genes with novel expression patterns, observations that peptide growth factors and retinoic acid influence homeobox gene expression, and the generation of mutant phenotypes of embryos homozygous for null mutations. These combined studies reinforce the idea that homeobox
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Recent highlights in vertebrate homeobox gene research include the discovery of new genes with novel expression patterns, observations that peptide growth factors and retinoic acid influence homeobox gene expression, and the generation of mutant phenotypes of embryos homozygous for null mutations. These combined studies reinforce the idea that homeobox
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Current Opinion in Genetics & Development, 1997
To date, not many disorders have been associated with homeobox genes, especially with those belonging to the HOX family. This is particularly surprising, considering the body of evidence accumulated for a role of these genes in the control of mammalian development.
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To date, not many disorders have been associated with homeobox genes, especially with those belonging to the HOX family. This is particularly surprising, considering the body of evidence accumulated for a role of these genes in the control of mammalian development.
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Organization of human homeobox genes
Human Reproduction, 1988The chromosomal localization of 17 human homeoboxes and the predicted primary sequence of the encoded homeodomains is reported. These homeoboxes are clustered in four complex HOX loci on chromosomes 2, 7, 12 and 17. Although the identification of human homeoboxes has not been completed, existing data permit preliminary conclusions on the origin and ...
Edoardo Boncinelli +6 more
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Homeobox genes and heart development
Trends in Cardiovascular Medicine, 1995Genes encoding transcription factors are fundamental to developmental processes because their DNA-binding proteins can control expression of a multitude of genes. Therefore, activation of a single transcription factor gene can act as a genetic switch that controls the developmental destinies of groups of cells.
M J, Kern, E A, Argao, S S, Potter
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Gradient fields and homeobox genes
Development, 1991ABSTRACT We review here old experiments that defined the existence of morphogenetic gradient fields in vertebrate embryos. The rather abstract idea of cell fields of organforming potential has become less popular among modern developmental and molecular biologists.
E M, De Robertis, E A, Morita, K W, Cho
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